Centre for Genomic Pathogen Surveillance

The Centre for Genomic Pathogen Surveillance is a computational genomics research institute in South Cambridgeshire.

Centre for Genomic Pathogen Resistance
CGPS
Location within Cambridgeshire
General information
TypeComputer Research Centre
AddressSouth Cambridgeshire
Coordinates52.0785°N 0.1863°E / 52.0785; 0.1863
Elevation15 m (49 ft)
Completed2015
OwnerWellcome Trust

History

The Centre for Genomic Pathogen Resistance opened in 2015. In 2017 it was announced that the centre will house a new Global Health Research Unit funded by the National Institute for Health Research (NIHR) to look at antibiotic resistance.[1][2] This has seen the centre becoming involved with surveillance of antibiotic resistance in a number of countries, for example, the Philippines.[3]

During the COVID-19 pandemic, the centre received significant further funding, including a £12.2m grant.[4]

Structure

The centre's director is David Aanensen.[5][6]

The centre is principally funded, and directed, by the Department of Health and Social Care.[7] In 2019, it was agreed that there would be collaboration between the Centre for Genomic Pathogen Surveillance, the European Centre for Disease Prevention and Control, and the Wellcome Sanger Institute, towards improving the monitoring and tracking of infectious diseases across Europe.[8]

Applications created at the centre

Under the auspices of the centre, the Epicollect5 (used for data entry from distributed observers, e.g. by 'citizen science' programs), Microreact,[9][10] and Pathogenwatch applications have been generated and shared.[5] Microreact[11] has seen extensive use during the COVID-19 pandemic, and is a component of the Phylogenetic Assignment of Named Global Outbreak Lineages (pangolin) software tool.[6][12][13]

Location

The centre is located at the Wellcome Sanger Institute in South Cambridgeshire.[8]

See also
  • List of phylogenetic tree visualization software
  • Microbial Genomics
  • Ineos Oxford Institute for AMR Research
  • Virus Pathogen Database and Analysis Resource

References
  1. Funding and Awards fundingawards.nihr.ac.uk, accessed 2 March 2021
  2. The Centre for Genomic Pathogen Surveillance to house the Global Health Research Unit to monitor antibiotic resistant bacteria around the globe 21 July 2017 www.sanger.ac.uk, accessed 7 March 2021
  3. Integrating whole-genome sequencing within the National Antimicrobial Resistance Surveillance Program in the Philippines 1 June 2020 www.nature.com, accessed 7 March 2021, DOI: 10.1038/s41467-020-16322-5
  4. Paul Brackley: £12.2m funding will help Cambridge-led COG-UK expand Covid-19 genomic surveillance 20 November 2020 www.cambridgeindependent.co.uk, accessed 8 March 2021
  5. Professor David Aanensen, Director of the Centre for Genomic Pathogen Surveillance and Group Leader www.sanger.ac.uk, accessed 7 March 2021
  6. David Aanensen Director of The Centre for Genomic Pathogen Surveillance 2021 www.ndm.ox.ac.uk, accessed 7 March 2021
  7. NIHR Home page www.nihr.ac.uk, accessed 2 March 2021
  8. Commitment to collaborate on using genomics for pathogen surveillance across Europe 14 March 2019 www.sanger.ac.uk, accessed 7 March 2021
  9. Hospitals in Europe are contributing to the spread of extremely drug-resistant bacteria 30 July 2019, www.zmescience.com, accessed 8 March 2021
  10. Superbug infections tracked across Europe 5 May 2016 www.sciencedaily.com, accessed 8 March 2021
  11. "Microreact has been developed by the Centre for Genomic Pathogen Surveillance at Imperial College London and the Wellcome Genome Campus" microreact.org, accessed 8 March 2021
  12. "Pangolin web application release". virological.org. May 2020. Retrieved 18 February 2021.
  13. How the Covid-19 Genomics UK Consortium sequenced Sars-Cov-2 12 April 2021 www.computerweekly.com, accessed 26 May 2021
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