Chorangiosis

Chorangiosis is a placental pathology characterized by an abundance of blood vessels within the chorionic villi.

Chorangiosis
Micrograph of a chorangiosis. H&E stain.
SpecialtyPathology

Associations

It is associated with gestational diabetes,[1] smoking and high altitude.

Diagnosis

It is diagnosed by a microscopic examination of the placenta.

Commonly used criteria from Altshuler[2][3] are: "a minimum of 10 villi, each with 10 or more vascular channels, in 10 or more areas of 3 or more random, non-infarcted placental areas when using a ×10 ocular." The Altshuler criteria are not theoretically rigorous, as they do not define the area. Normal villi have up to five vascular channels.[3]

See also

Additional images
  • Intermed. mag.
  • Very high mag.

References
  1. Daskalakis, G.; Marinopoulos, S.; Krielesi, V.; Papapanagiotou, A.; Papantoniou, N.; Mesogitis, S.; Antsaklis, A. (2008). "Placental pathology in women with gestational diabetes". Acta Obstet Gynecol Scand. 87 (4): 403–7. doi:10.1080/00016340801908783. PMID 18382864. S2CID 43058233.
  2. Altshuler, G. (Jan 1984). "Chorangiosis. An important placental sign of neonatal morbidity and mortality". Arch Pathol Lab Med. 108 (1): 71–4. PMID 6546343.
  3. De La Ossa, MM.; Cabello-Inchausti, B.; Robinson, MJ. (Sep 2001). "Placental chorangiosis". Arch Pathol Lab Med. 125 (9): 1258. doi:10.5858/2001-125-1258-PC. PMID 11520290.
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