Dementia with Lewy Bodies Consortium

The Dementia with Lewy Bodies Consortium (DLB Consortium or DLBC) is an international multidisciplinary collaboration of researchers interested in the dementia with Lewy bodies.[1] It first convened in Newcastle upon Tyne, England, in October 1995.[1] Between 1995 and 2005, it issued three DLBC Consensus Reports on dementia with Lewy bodies.[2]

Fourth Consensus Report

The 2017 rewrite of the diagnostic criteria for DLB[3] was led by Ian G. McKeith of Newcastle University and supported by The National Institute on Aging, National Institutes of Neurological Disorders and Stroke, the Lewy Body Dementia Association, the Lewy Body Society, Alzheimer’s Association, Acadia Pharmaceuticals, Axovant Sciences, Banner Health, GE Healthcare, and Lundbeck.[4]

DLBC 2015

The 2015 DLBC in the United States is a project of the Parkinson's Disease BioMarker Program of the National Institute of Neurological Disorders and Stroke that "establishes a group of centers dedicated to the study of dementia with Lewy bodies (DLB) ... to allow for the discovery of a biomarker for DLB to improve the diagnosis, care, and treatment of patients with this disease".[5]

As of 2020, it includes nine centers that have Lewy body dementia experts who have "strong connections to the Lewy body dementia research and general community".[5] The DLBC will "formalize and strengthen already existing collaboration among the participating centers".[6] The nine centers as of 2018 are:[5]

  • Cleveland Clinic
  • Florida Atlantic University
  • Thomas Jefferson University
  • Rush University
  • University of California San Diego
  • University of North Carolina
  • University of Pennsylvania
  • University of Pittsburgh
  • VA Puget Sound Health Care System - University of Washington

The DLBC is funded by a "$6 million, five-year grant from the National Institutes of Health";[6] it was also funded by the Lewy Body Dementia Association and GE Healthcare.[6]

Sources
  • McKeith IG (2017). "Chapter 5: Clinical diagnostic criteria for dementia with Lewy bodies". In Kosaka K (ed.). Dementia with Lewy bodies: clinical and biological aspects (1st ed.). Japan: Springer. doi:10.1007/978-4-431-55948-1. ISBN 978-4-431-55948-1.

References
  1. McKeith IG in Kosaka K, ed. (2017), pp. 63–64.
  2. McKeith IG in Kosaka K, ed. (2017), pp. 64–67.
  3. McKeith IG, Boeve BF, Dickson DW, et al. (July 2017). "Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium". Neurology (Review). 89 (1): 88–100. doi:10.1212/WNL.0000000000004058. PMC 5496518. PMID 28592453.
  4. "New Diagnostic Criteria Published for DLB". Lewy Body Dementia Association, Inc. 2016. Retrieved March 22, 2018.
  5. "Dementia with Lewy Bodies Consortium (U01): Summary". Parkinson's Disease Biomarker Program. National Institute of Neurological Disorders and Stroke. Retrieved May 14, 2020.
  6. Leverenz, James and Babak Tousi (October 2, 2017). "New Research Consortium Gives Dementia with Lewy Bodies Its Due" (Press release). Cleveland Clinic. Retrieved March 22, 2018. Also Press release
  • Official website of US DLBC
  • McKeith IG (2006). "Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop". J. Alzheimers Dis. 9 (3 Suppl): 417–23. doi:10.3233/JAD-2006-9S347. PMID 16914880.
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