Dhori virus
Dhori virus (DHOV) is a species of the genus Thogotovirus and a member of the family Orthomyxoviridae. Its hosts are ticks, mosquitoes, and mammals (including humans). DHOV is lethal to mice, causing systemic pathologic changes similar to those reported in humans with virulent influenza A (H5N1) virus infection.[1]
Dhori thogotovirus | |
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Virus classification | |
(unranked): | Virus |
Realm: | Riboviria |
Kingdom: | Orthornavirae |
Phylum: | Negarnaviricota |
Class: | Insthoviricetes |
Order: | Articulavirales |
Family: | Orthomyxoviridae |
Genus: | Thogotovirus |
Species: | Dhori thogotovirus |
Serotypes | |
Batken virus |
Batken virus (BKNV) is considered a subtype of DHOV. Serological cross-reactions between BKNV and DHOV indicate a phylogenetic relationship between these viruses.[2]
References
- Li G, Wang N, Guzman H, Sbrana E, Yoshikawa T, Tseng CT, Tesh RB, Xiao SY (2008). "Dhori virus (Orthomyxoviridae: Thogotovirus) infection of mice produces a disease and cytokine response pattern similar to that of highly virulent influenza A (H5N1) virus infection in humans". Am. J. Trop. Med. Hyg. 78 (4): 675–80. doi:10.4269/ajtmh.2008.78.675. PMID 18385368.
- Frese M, Weeber M, Weber F, Speth V, Haller O (1997). "Mx1 sensitivity: Batken virus is an orthomyxovirus closely related to Dhori virus". J. Gen. Virol. 78 ( Pt 10) (10): 2453–8. doi:10.1099/0022-1317-78-10-2453. PMID 9349464.
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