Diamocaine

Diamocaine is a local anesthetic that was developed by Janssen Pharmaceuticals in the 1970s. It is a 4-phenylpiperidine derivative, structurally related to opioid drugs such as piminodine and antipsychotics such as haloperidol, but in this series only local anesthetics were produced.[1]

Diamocaine
Identifiers
IUPAC name
  • N-[2-[4-[2-(diethylamino)ethoxy]-4-phenylpiperidin-1-yl]ethyl]aniline
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC25H37N3O
Molar mass395.591 g·mol−1
3D model (JSmol)
SMILES
  • CCN(CC)CCOC1(CCN(CC1)CCNC2=CC=CC=C2)C3=CC=CC=C3
InChI
  • InChI=1S/C25H37N3O/c1-3-27(4-2)21-22-29-25(23-11-7-5-8-12-23)15-18-28(19-16-25)20-17-26-24-13-9-6-10-14-24/h5-14,26H,3-4,15-22H2,1-2H3
  • Key:JSELIWGNAHBPAE-UHFFFAOYSA-N

See also

References
  1. Hermans B, Verhoeven H, Janssen P (September 1970). "4-substituted piperidines. V. Local anesthetic 4-aminoalkoxy-4-arylpiperidines". Journal of Medicinal Chemistry. 13 (5): 835–8. doi:10.1021/jm00299a009. PMID 5458366.


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