Jaccoud arthropathy

Jaccoud arthropathy (JA), is a chronic non-erosive reversible joint disorder that may occur after repeated bouts of arthritis.[1][2] It is caused by inflammation of the joint capsule and subsequent fibrotic retraction, causing ulnar deviation of the fingers, through metacarpophalangeal joint (MCP) subluxation,[1][3] primarily of the ring and little-finger.[3] Joints in the feet, knees and shoulders may also get affected.[1] It is commonly associated with systemic lupus erythematosus (SLE), and occurs in roughly 5% of all cases.[1][2]

Jaccoud arthropathy
Other namesJaccoud deformity or Jaccoud's arthopathy
Jaccoud arthropathy seen on a hand x-ray. As opposed to arthropathy due to rheumatoid arthritis, there are no erosions.
SpecialtyRheumatology 

When associated with rheumatic fever it is also called chronic post–RF arthropathy.[3]

Presentation

Associated conditions

Originally thought to be associated only with rheumatic fever, it has since been shown to occur also in SLE, Sjögren syndrome, scleroderma, dermatomyositis, psoriatic arthritis, vasculitis, ankylosing spondylitis, mixed connective tissue disease, and pyrophosphate deposition disease.[1] It is distinct from bone erosion which is commonly associated with rheumatic arthritis,[1] and also distinct from mild deforming arthropathy which is associated with SLE.[2] There have also been cases of non-rheumatic JA associated with Lyme disease, HIV-infection and a number of other conditions.[1]

Diagnosis

Plain hand radiographs typically show marked ulnar subluxation and deviation at the metacarpophalangeal joints. Absence of erosions is a notable feature, although occasionally "hook" erosions may be observed, which are similar to those seen in SLE and ankylosing spondylitis. Evidence of muscle (soft tissue) atrophy also may be present.

Treatment

The focus of treatment is toward alleviating pain and maintaining functionality of the affected joints through use of nonsteroidal anti-inflammatory drugs, corticosteroids, antimalarial drugs and physiotherapy.[1] Surgery is also a possibility, with osteotomy or stabilization with Kirschner intramedullary wire.[1] Tendon relocation, however, has been shown to only work in 30% of cases.[1] The condition is named after the French 19th century physician Sigismond Jaccoud.[4]

See also

References
  1. Santiago, Mittermayer B. (2011-10-01). "Miscellaneous non-inflammatory musculoskeletal conditions. Jaccoud's arthropathy". Best Practice & Research. Clinical Rheumatology. 25 (5): 715–725. doi:10.1016/j.berh.2011.10.018. ISSN 1532-1770. PMID 22142749.
  2. Pipili, Chrisoula; Sfritzeri, Areti; Cholongitas, Evangelos (2008-11-01). "Deforming arthropathy in systemic lupus erythematosus". European Journal of Internal Medicine. 19 (7): 482–487. doi:10.1016/j.ejim.2008.01.017. ISSN 1879-0828. PMID 19013374.
  3. Hochberg, Marc C. (2014). Rheumatology. Mosby. p. 922. ISBN 978-0323091381.
  4. Jaccoud, Sigismond (1867-01-01). Leçons de clinique médicale :faites a l'hôpital de la Charité /. Paris. hdl:2027/ucm.5323258121.
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