Medication appropriateness tool for co‐morbid health conditions in dementia criteria

The Medication Appropriateness Tool for Comorbid Health conditions during Dementia (MATCH-D) criteria supports clinicians to manage medication use specifically for people with dementia without focusing only on the management of the dementia itself.[1][2]

History

The MATCH-D were developed by medical practitioners and pharmacists at Australian Group of Eight Universities. It was led by Dr Amy Theresa Page at the Western Australian Centre for Health and Ageing at the University of Western Australia. The MATCH-D Criteria were developed through a consensus panel of experts using the Delphi method. The criteria were originally published in the Internal Medicine Journal in 2016.[2] The protocol explaining the rigorous methods used to develop the criteria were originally published in the BMJ Open in 2015.[3] The systematic review that informed the criteria were published subsequently in 2018 and updated in 2022.[4] [5]

Style of the criteria

The MATCH-D is presented in categories of recommendations for all stages of dementia, as well as divided into specific recommendations for early, mid and late-stage dementia. The recommendations are groups as: medication side effects, principles for medication use, medication review, treatment goals, preventative medications, symptom management, psycho-active medications, medications to modify dementia progression.

Reception of the criteria

The MATCH-D attracted media attention as it was under development, and as it was released. Page was interviewed on the ABC national radio's science show during its development.[6] The health media picked up the story as soon as it was published.[7] Respected organisations such as the New South Wales' Therapeutic Advisory Group (TAG) highlighted the importance of the work in their newsletters.

Uses

Consumers considered the MATCH-D to be a useful tool for prompting and supporting conversations about their preferences for medication use. They would prefer that these conversations began as early as possible so that their treating health professionals knew their preferences. General practitioners, pharmacists and nurses stated they often felt less comfortable discussing these issues as they were concerned that it may cause distress to the consumer. Health professionals and consumers alike thought that using the MATCH-D as a conversation starter could assist with these conversations.[8]


It is cited and promoted by influential national international bodies including:

- the British Geriatrics Society's End of Life Care in Frailty guidelines[9]

- Australia's RACGP aged care clinical guide known as the Silver Book[10]

- New Zealand's Health Quality & Safety Commission's medication management work [11]

Research on the criteria

Translational research was undertaken with consumers, general practitioners, nurses and pharmacists to explore the enablers and barriers to using the MATCH-D in practice.[8] This research showed the need for a website (since launched at MATCH-D.com.au), checklists (available at the website) and educational resources. These stakeholder roles have shown that there is a strong need for support and collaboration to improve medication use.[12]

The National Health and Medical Research Council (NHMRC) are currently funding a randomised controlled trial implementing the MATCH-D using pharmacists embedded in general practice.[13]

Educational resources

The Dementia Training Australia funding an interactive online education package for deprescribing in dementia centered around the MATCH-D. It was a joint collaboration between the University of Western Australia, University of Tasmania, La Trobe University, Monash University, Alfred Health and FireFilms. This education package launched in mid-2019.[14] This online course is suitable for consumers and health professionals, with a target audience of nurses working in residential aged care facilities. The training package was in the format of a documentary film, with its original developer, Dr Page featured as narrator and interviewer. It includes simulated patient encounters and expert interviews, interspersed with interactive activities.

References

  1. "MATCH-D Medication Appropriateness Tool for Comorbid Health conditions during Dementia". www.match-d.com.au. Retrieved 2019-06-01.
  2. Page, A. T.; Potter, K.; Clifford, R.; McLachlan, A. J.; Etherton‐Beer, C. (2016). "Medication appropriateness tool for co-morbid health conditions in dementia: consensus recommendations from a multidisciplinary expert panel". Internal Medicine Journal. 46 (10): 1189–1197. doi:10.1111/imj.13215. PMC 5129475. PMID 27527376.
  3. Etherton-Beer, Christopher; McLachlan, Andrew; Clifford, Rhonda; Potter, Kathleen; Page, Amy (2015-08-01). "Prescribing for Australians living with dementia: study protocol using the Delphi technique". BMJ Open. 5 (8): e008048. doi:10.1136/bmjopen-2015-008048. PMC 4538244. PMID 26264272.
  4. Page, Amy; Etherton‐Beer, Christopher; Seubert, Liza J.; Clark, Vaughan; Hill, Xaysja; King, Stephanie; Clifford, Rhonda M. (2018). "Medication use to manage comorbidities for people with dementia: a systematic review". Journal of Pharmacy Practice and Research. 48 (4): 356–367. doi:10.1002/jppr.1403.
  5. Wang, Kate; Alan, Janine; Page, Amy; Percival, Mia; Etherton‐Beer, Christopher (2022). "Medication use to manage comorbidities in people with dementia: A systematic review". Journal of Pharmacy Practice and Research. doi:10.1002/jppr.1802. S2CID 247574884.
  6. "Reducing the burden of multiple medicines for older dementia patients". Radio National. 2015-05-22. Retrieved 2019-06-01.
  7. "MATCH-D study gains consensus on dementia medicines management". AJP. 2016-08-17. Retrieved 2019-06-01.
  8. Etherton-Beer, Christopher D.; Parekh, Nikesh; Ryan, Cristin; Clark, Vaughan; King, Stephanie; Hill, Xaysja; McLachlan, Andrew J.; Seubert, Liza; Potter, Kathleen (2017-08-01). "Exploring the enablers and barriers to implementing the Medication Appropriateness Tool for Comorbid Health conditions during Dementia (MATCH-D) criteria in Australia: a qualitative study". BMJ Open. 7 (8): e017906. doi:10.1136/bmjopen-2017-017906. PMC 5724063. PMID 28838905.
  9. "End of Life Care in Frailty: Medicines management". British Geriatrics Society. Retrieved 2022-02-03.
  10. RACGP aged care clinical guide (Silver Book) 5th Edition. Royal Australian College of General Practitioners.
  11. "Health Quality & Safety Commission NZ" (PDF).{{cite web}}: CS1 maint: url-status (link)
  12. Cross, Amanda J.; Etherton-Beer, Christopher D.; Clifford, Rhonda M.; Potter, Kathleen; Page, Amy T. (1 April 2021). "Exploring stakeholder roles in medication management for people living with dementia". Research in Social and Administrative Pharmacy. 17 (4): 707–714. doi:10.1016/j.sapharm.2020.06.006. PMID 33722353. S2CID 219923285.
  13. "ANZCTR - Registration".
  14. "Too much of a good thing: fundamentals of deprescribing". DTA. 2020-07-24. Retrieved 2021-04-08.
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