Mizuo–Nakamura phenomenon

The Mizuo–Nakamura Phenomenon is a phenomenon observed in Oguchi's disease.[1] It was named after Gentaro Mizuo (1876–1913) and Bunpei Nakamura (1886–1969), Japanese ophthalmologists.

Oguchi disease is characterized by a golden-brown fundus with a yellow-gray 'metallic' sheen in the light-adapted state. After complete dark adaptation (3 to 12 hours), the fundus appears normal, and this disappearance of the shiny, yellow, fundus reflex is called the Mizuo–Nakamura phenomenon.

References

Takada, M.; Otani, A.; Ogino, K.; Yoshimura, N. (2011). "Spectral-Domain Optical Coherence Tomography Findings in the Mizuo–Nakamura Phenomenon of Oguchi Disease". Retina. 31 (3): 626–628. doi:10.1097/IAE.0b013e318206cd52. PMID 21336075.

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[1] Takada, M.; Otani, A.; Ogino, K.; Yoshimura, N. (2011). "Spectral-Domain Optical Coherence Tomography Findings in the Mizuo–Nakamura Phenomenon of Oguchi Disease". Retina. 31 (3): 626–628. doi:10.1097/IAE.0b013e318206cd52. PMID 21336075.