Mucrocetin
Mucrocetin is a snake venom platelet-agglutinating factor, that acts in a vWF-independent manner. It binds specifically to platelet GPIbalpha (GP1BA) to a distinct binding site from that of flavocetin-A. It is isolated from the venom of Taiwan habu (Protobothrops mucrosquamatus).[1]
| mucrocetin, subunit A | |||||||
|---|---|---|---|---|---|---|---|
 Mucrocetin hetero24mer (A+B) | |||||||
| Identifiers | |||||||
| Organism | |||||||
| Symbol | ? | ||||||
| PDB | 1v4l | ||||||
| UniProt | Q6TPH0 | ||||||
| |||||||
| mucrocetin, subunit B | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Organism | |||||||
| Symbol | ? | ||||||
| PDB | 1v4l | ||||||
| UniProt | Q6TPG9 | ||||||
| |||||||
It is related to the C-type lectins.
References
- Huang KF, Ko TP, Hung CC, Chu J, Wang AH, Chiou SH (March 2004). "Crystal structure of a platelet-agglutinating factor isolated from the venom of Taiwan habu (Trimeresurus mucrosquamatus)". The Biochemical Journal. 378 (Pt 2): 399–407. doi:10.1042/BJ20031507. PMC 1223962. PMID 14613481.
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