Phenamidine

Phenamidine
Clinical data
Trade names	Oxopirvedine
Other names	4,4'-Diamidinodiphenyl ether; 4,4'-Oxydibenzamidine
ATCvet code	QP51AF03 (WHO) ;
Identifiers
	IUPAC name 4,4’-Oxydibenzenecarboximidamide;
CAS Number	101-62-2;
PubChem CID	64948;
ChemSpider	58474;
UNII	382086V7IB;
CompTox Dashboard (EPA)	DTXSID10143619 ;
ECHA InfoCard	100.002.692
Chemical and physical data
Formula	C14H14N4O
Molar mass	254.293 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	215 to 216 °C (419 to 421 °F) [1]
	SMILES O(c1ccc(C(=[N@H])N)cc1)c2ccc(cc2)C(=[N@H])N;
	InChI InChI=1S/C14H14N4O/c15-13(16)9-1-5-11(6-2-9)19-12-7-3-10(4-8-12)14(17)18/h1-8H,(H3,15,16)(H3,17,18); Key:DMABBVCVVXMJDH-UHFFFAOYSA-N;

Phenamidine is an antiprotozoal drug of the amidine class used in veterinary medicine. It is used to treat Babesia infection (babesiosis) dogs, horses, and cattle.[1][2] Because the drug causes frequent allergic reactions, it is usually combined with an antihistamine.

References

Merck Index, 11th Edition, 7165
Randall JB, Laws SG (May 1947). "Phenamidine in the treatment of Babesia bigemina infections of cattle". Annals of Tropical Medicine and Parasitology. 41 (1): 39–42. doi:10.1080/00034983.1947.11685310. PMID 20249289.

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[Merck-1] Merck Index, 11th Edition, 7165

[pmid20249289-2] Randall JB, Laws SG (May 1947). "Phenamidine in the treatment of Babesia bigemina infections of cattle". Annals of Tropical Medicine and Parasitology. 41 (1): 39–42. doi:10.1080/00034983.1947.11685310. PMID 20249289.