Placental villous immaturity

Placental villous immaturity is chorionic villous development that is inappropriate for the gestational age.

Placental villous immaturity
Other namesVillous immaturity, villous dysmaturity
Micrograph of villous immaturity. H&E stain.
SpecialtyGynecology, pathology

It is associated with diabetes mellitus[1] and fetal death near term, i.e. intrauterine demise close to the normal gestational period.[2]

Pathology

Immature chorionic villi are larger and have more central blood vessels; thus, the diffusion distance for gas and nutrient exchange is larger and, therefore, placental function is impaired.

See also

References

  1. Arizawa, M.; Nakayama, M.; Kidoguchi, K. (Jun 1991). "[Correlation of placental villous immaturity and dysmaturity with clinical control of maternal diabetes]". Nihon Sanka Fujinka Gakkai Zasshi. 43 (6): 595–602. PMID 1856519.
  2. Stallmach, T.; Hebisch, G. (Jul 2004). "Placental pathology: its impact on explaining prenatal and perinatal death" (PDF). Virchows Arch. 445 (1): 9–16. doi:10.1007/s00428-004-1032-2. PMID 15138817.
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