Quinapyramine

Quinapyramine is a trypanocidal agent for veterinary use.[1][2]

Quinapyramine
Clinical data
ATCvet code
Identifiers
IUPAC name
  • N'-(4-imino-1,2-dimethyl-6-quinolyl)-1,6-dimethylpyrimidin-1-ium-2,4-diamine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC17H21N6+
Molar mass309.397 g·mol−1
3D model (JSmol)
SMILES
  • CC1=CC(=N)C2=C(N1C)C=CC(=C2)NC3=NC(=[N+](C(=C3)C)C)N
InChI
  • InChI=1S/C17H20N6/c1-10-7-14(18)13-9-12(5-6-15(13)22(10)3)20-16-8-11(2)23(4)17(19)21-16/h5-9,18H,1-4H3,(H2,19,20,21)/p+1/b18-14+
  • Key:KMJWBVJQFGRCEB-NBVRZTHBSA-O
  (verify)

References
  1. Hawking F, Sen AB (December 1960). "The trypanocidal action of homidium, quinapyramine and suramin". British Journal of Pharmacology and Chemotherapy. 15 (4): 567–70. doi:10.1111/j.1476-5381.1960.tb00283.x. PMC 1482270. PMID 13712404.
  2. Ranjithkumar M, Saravanan BC, Yadav SC, Kumar R, Singh R, Dey S (February 2014). "Neurological trypanosomiasis in quinapyramine sulfate-treated horses--a breach of the blood-brain barrier?". Tropical Animal Health and Production. 46 (2): 371–7. doi:10.1007/s11250-013-0498-9. PMID 24197687. S2CID 16060891.
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