Sclerosis (medicine)

Sclerosis (from Greek σκληρός sklērós, "hard") is the stiffening of a tissue or anatomical feature, usually caused by a replacement of the normal organ-specific tissue with connective tissue. The structure may be said to have undergone sclerotic changes or display sclerotic lesions, which refers to the process of sclerosis.

Sclerosis
Other namesSclerosus
Micrograph of subepithelial sclerosus (middle third of image) in a case of lichen sclerosus. H&E stain.

Common medical conditions whose pathology involves sclerosis include:

References

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