Sereny test

The Sereny test is a test used to test the invasiveness of enteroinvasive Escherichia coli, Shigella species, and Listeria monocytogenes.[1][2][3]

It is done by inoculating suspension of bacteria into guinea pig's eye. Severe mucopurulent conjunctivitis and severe keratitis indicates a positive test.[3]

References
  1. Wood PK, Morris JG, Small PL, et al. (September 1986). "Comparison of DNA probes and the Sereny test for identification of invasive Shigella and Escherichia coli strains". J. Clin. Microbiol. 24 (3): 498–500. doi:10.1128/jcm.24.3.498-500.1986. PMC 268950. PMID 3531233.
  2. Murayama SY, Sakai T, Makino S, Kurata T, Sasakawa C, Yoshikawa M (February 1986). "The use of mice in the Sereny test as a virulence assay of shigellae and enteroinvasive Escherichia coli". Infect. Immun. 51 (2): 696–8. doi:10.1128/iai.51.2.696-698.1986. PMC 262412. PMID 3510985.
  3. Jay JM (1995). Modern Food Microbiology (5 ed.). p. 262. ISBN 978-1-4615-7476-7. Retrieved 21 April 2018.
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