Streptomyces tsukubensis
Streptomyces tsukubensis is a bacterium species from the genus of Streptomyces which has been isolated from soil in Ibaraki in Japan.[1][3][4] Streptomyces tsukubensis produces the immunosuppressant tacrolimus.[4][5]
| Streptomyces tritolerans | |
|---|---|
| Scientific classification | |
| Domain: | Bacteria |
| Phylum: | |
| Class: | |
| Order: | |
| Family: | |
| Genus: | |
| Species: | S. tritolerans |
| Binomial name | |
| Streptomyces tritolerans Muramatsu and Nagai 2013[1] | |
| Type strain | |
| 9993, DSM 42081, NBRC 108819, NBRC 108919[2] | |
| Synonyms | |
| |
See also
References
- LPSN bacterio.net
- Straininfo of Streptomyces tsukubensis
- UniProt
- Deutsche Sammlung von Mikroorganismen und Zellkulturen
- Oliver, Kayser (2002). Grundwissen Pharmazeutische Biotechnologie. Wiesbaden: Vieweg+Teubner Verlag. ISBN 3-322-80124-1.
Further reading
- Chen, D.; Zhang, Q.; Zhang, Q.; Cen, P.; Xu, Z.; Liu, W. (11 May 2012). "Improvement of FK506 Production in Streptomyces tsukubaensis by Genetic Enhancement of the Supply of Unusual Polyketide Extender Units via Utilization of Two Distinct Site-Specific Recombination Systems". Applied and Environmental Microbiology. 78 (15): 5093–5103. doi:10.1128/AEM.00450-12. PMC 3416438. PMID 22582065.
- Barreiro, C; Prieto, C; Sola-Landa, A; Solera, E; Martínez-Castro, M; Pérez-Redondo, R; García-Estrada, C; Aparicio, JF; Fernández-Martínez, LT; Santos-Aberturas, J; Salehi-Najafabadi, Z; Rodríguez-García, A; Tauch, A; Martín, JF (July 2012). "Draft genome of Streptomyces tsukubaensis NRRL 18488, the producer of the clinically important immunosuppressant tacrolimus (FK506)". Journal of Bacteriology. 194 (14): 3756–7. doi:10.1128/jb.00692-12. PMC 3393489. PMID 22740677.
- Goranovič, Dušan; Blažič, Marko; Magdevska, Vasilka; Horvat, Jaka; Kuščer, Enej; Polak, Tomaž; Santos-Aberturas, Javier; Martínez-Castro, Miriam; Barreiro, Carlos; Mrak, Peter; Kopitar, Gregor; Kosec, Gregor; Fujs, Štefan; Martín, Juan F; Petković, Hrvoje (2012). "FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensis". BMC Microbiology. 12 (1): 238. doi:10.1186/1471-2180-12-238. PMC 3551636. PMID 23083511.
- Xia, Menglei; Huang, Di; Li, Shanshan; Wen, Jianping; Jia, Xiaoqiang; Chen, Yunlin (October 2013). "Enhanced FK506 production in by rational feeding strategies based on comparative metabolic profiling analysis". Biotechnology and Bioengineering. 110 (10): 2717–2730. doi:10.1002/bit.24941. PMID 23682004. S2CID 24059003.
External links
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