Surgical sealant film

A surgical sealant film is an implantable medical device used during surgery. It is a preformed flexible patch that is applied to supplement sutures and surgical staples to seal tissues and prevent leaks of fluid (including blood and cerebrospinal fluid) and air.

Use of a surgical sealant film to reinforce and seal gaps in the dura mater.

The sealant film is synthetic and incorporates absorbable polymers, including poly(lactide-co-glycolide). The polymeric components impart structural and adhesive properties with the sealing effect achieved by incorporation of a bioadhesive polymer. This forms a covalent bond to primary amines present on the tissue surfaces. In turn this results in the film rapidly becoming effective in providing a form of secondary wound closure.[1][2]

The film can be used for sealing the dura mater,[3][4][5] preventing blood loss in general surgery and eliminating air leaks following lung resection.

References
  1. Cheng, L; Lau, CK; Parker, G (Oct 14, 2013). "Use of TissuePatch™ sealant film in the management of chyle leak in major neck surgery". The British Journal of Oral & Maxillofacial Surgery. 52 (1): 87–9. doi:10.1016/j.bjoms.2013.09.007. PMID 24135151.
  2. Cheng, LH; Hutchison, IL (October 2012). "Thyroid surgery". The British Journal of Oral & Maxillofacial Surgery. 50 (7): 585–91. doi:10.1016/j.bjoms.2011.11.002. PMID 22192610.
  3. Ferroli, P; Acerbi, F; Broggi, M; Schiariti, M; Albanese, E; Tringali, G; Franzini, A; Broggi, G (Mar–Apr 2013). "A novel impermeable adhesive membrane to reinforce dural closure: a preliminary retrospective study on 119 consecutive high-risk patients". World Neurosurgery. 79 (3–4): 551–7. doi:10.1016/j.wneu.2011.09.022. PMID 22120260.
  4. von der Brelie, C; Soehle, M; Clusmann, HR (April 2012). "Intraoperative sealing of dura mater defects with a novel, synthetic, self adhesive patch: application experience in 25 patients". British Journal of Neurosurgery. 26 (2): 231–5. doi:10.3109/02688697.2011.619597. PMID 22077588. S2CID 23604838.
  5. Della Puppa, A; Rossetto, M; Scienza, R (October 2010). "Use of a new absorbable sealing film for preventing postoperative cerebrospinal fluid leaks: remarks on a new approach". British Journal of Neurosurgery. 24 (5): 609–11. doi:10.3109/02688697.2010.500413. PMID 20868249. S2CID 10468526.
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