Trotter's syndrome

Trotter's syndrome is a cluster of symptoms associated with certain types of advanced nasopharyngeal carcinoma. The cause of pain is the mandibular nerve of the foramen ovale, through which the tumor enters the calvarium.[1] Symptoms include the following:[2]

  1. Unilateral conductive deafness due to middle ear effusion
  2. Trigeminal neuralgia due to perineural spread
  3. Soft palate immobility
  4. Difficulty opening mouth

References
  1. Rajendran, Arya; Sivapathasundharam, B. (2014). Shafer's Textbook of Oral Pathology. Elsevier Health Sciences. p. 854. ISBN 9788131238004.
  2. Lucente, Frank E.; Har-El, Gady (2004). Essentials of Otolaryngology. Lippincott Williams & Wilkins. p. 156. ISBN 9780781747073.
  • Reiter S, Gavish A, Winocur E, Emodi-Perlman A, Eli I (2006). "Nasopharyngeal carcinoma mimicking a temporomandibular disorder: a case report". J Orofac Pain. 20 (1): 74–81. PMID 16483023.
  • Van Hassel HJ, Topping JW (July 1977). "Trotter's syndrome. A review". Oral Surg. Oral Med. Oral Pathol. 44 (1): 125–7. doi:10.1016/0030-4220(77)90253-5. PMID 267870.


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