Vaccitech

Vaccitech plc is a biotechnology company developing vaccines and immunotherapies for infectious diseases and cancer, such as hepatitis B, HPV and prostate cancer.[1][2]

Vaccitech plc
TypePublic
Traded as
Nasdaq: VACC
IndustryVaccines
Immunotherapy
Biotechnology
Founded2016 (2016)
Founder
  • Sarah Gilbert
  • Adrian V. S. Hill
Headquarters
Oxford Science Park, Oxford
,
United Kingdom
Websitevaccitech.co.uk

Technology

The company's platform includes Chimpanzee Adenovirus Oxford (ChAdOx) and Modified Vaccinia Ankara (MVA), two viral vectors which safely mimic viral infection in human cells and elicit antibody and T cell responses to pathogens and tumours.[3]

History

The company was founded in 2016 as a University spin-off by Sarah Gilbert and Adrian V. S. Hill at The Jenner Institute, University of Oxford.[4][5][6]

Vaccitech has been financed and supported by Google Ventures (GV), Fosun International, Tencent, Huawei, Sequoia Capital, GeneMatrix, Liontrust Asset Management, Korea Investment Partners and Oxford Sciences Innovation (OSI).[7][8]

In early 2020, Vaccitech and the University of Oxford co-invented a vaccine for COVID-19 using the ChAdOx platform.

COVID-19 vaccine

In July 2020, it was reported that people in Brazil, South Africa and the US had been recruited to populate the vaccine trials.[9]

In July 2020, Vaccitech scientists reported in The Lancet a "single-blind, randomised controlled trial in five trial sites in the UK of a chimpanzee adenovirus-vectored vaccine (ChAdOx1 nCoV-19) expressing the SARS-CoV-2 spike protein." Several subjects needed prophylactic paracetamol to minimize their adverse reactions.

References
  1. Vaccitech on Twitter
  2. Anon (2016). "Vaccitech Limited". companieshouse.gov.uk. London: Companies House.
  3. Anon (2019). "Vaccitech - Creating ways to treat and prevent disease". vaccitech.co.uk. Vaccitech Limited.
  4. Anon (2019). "Vaccitech Ltd". bloomberg.com. Bloomberg News.
  5. Anon (2016). "Universal flu vaccine under development by Oxford spinout Vaccitech". ox.ac.uk. University of Oxford.
  6. Anon (2019). "Vaccitech secures £20m Series A with GV, OSI and Sequoia China". innovation.ox.ac.uk. Oxford University Innovation.
  7. Anon (2019). "About Vaccitech". vaccitech.co.uk. Vaccitech Limited.
  8. "Inside the Chinese companies developing a Covid-19 vaccine".
  9. Boseley, Sarah (1 July 2020). "Oxford offers best hope for Covid-19 vaccine this year, MPs told". Guardian News & Media Limited.
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