Whole brain radiotherapy

Whole brain radiotherapy
Whole brain radiotherapy
Specialty	oncology

Whole brain radiotherapy (WBRT) is a palliative option for patients with brain metastases that alleviates symptoms, decreases the use of corticosteroids needed to control tumor-associated edema, and potentially improves overall survival.[1]

Usage

Whole brain radiotherapy (WBRT) has been reported to increase the risk of cognitive decline.[2]

WBRT is sometimes used along with stereotactic radiosurgery (SRS) or surgery, and while these can improve survival for some patients with single brain metastasis, a 2021 systematic review of the literature found inconsistent results for overall survival.[3]

References

McTyre, E; Scott, J; Chinnaiyan, P (2013). "Whole brain radiotherapy for brain metastasis". Surg Neurol Int. 4 (5): S236–44. doi:10.4103/2152-7806.111301. PMC 3656558. PMID 23717795.
"Whole-Brain Radiotherapy: Risks Worth Benefit?". Medscape.com. Retrieved August 20, 2015.
Garsa, Adam; Jang, Julie K.; Baxi, Sangita; Chen, Christine; Akinniranye, Olamigoke; Hall, Owen; Larkin, Jody; Motala, Aneesa; Newberry, Sydne; Hempel, Susanne (2021). "Radiation Therapy for Brain Metastases | Effective Health Care (EHC) Program". effectivehealthcare.ahrq.gov. doi:10.23970/ahrqepccer242. PMID 34152714. S2CID 236256085. Retrieved 2022-07-30.

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[MyUser_Ncbi.nlm.nih.gov_August_20_2015c-1] McTyre, E; Scott, J; Chinnaiyan, P (2013). "Whole brain radiotherapy for brain metastasis". Surg Neurol Int. 4 (5): S236–44. doi:10.4103/2152-7806.111301. PMC 3656558. PMID 23717795.

[MyUser_Medscape.com_August_20_2015c-2] "Whole-Brain Radiotherapy: Risks Worth Benefit?". Medscape.com. Retrieved August 20, 2015.

[3] Garsa, Adam; Jang, Julie K.; Baxi, Sangita; Chen, Christine; Akinniranye, Olamigoke; Hall, Owen; Larkin, Jody; Motala, Aneesa; Newberry, Sydne; Hempel, Susanne (2021). "Radiation Therapy for Brain Metastases | Effective Health Care (EHC) Program". effectivehealthcare.ahrq.gov. doi:10.23970/ahrqepccer242. PMID 34152714. S2CID 236256085. Retrieved 2022-07-30.