Earle may refer to:
- Franklin Sumner Earle (Earle) (1856-1929) - U.S. mycologist
- John L. Earle - U.S. ichthyologist
- Sylvia Alice Earle (S.A.Earle) (1935–) - phycologist
- W. Hubert Earle (W.H.Earle) (1906-1984) - Botanist
- William Earle - Entomologist
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