anxiogenic

anxio- +‎ -genic

anxiogenic (comparative more anxiogenic, superlative most anxiogenic)

1. Causing anxiety, or pertaining to the causing of anxiety.
   • 1997 June 27, “Activation of Corticotropin-Releasing Factor in the Limbic System During Cannabinoid Withdrawal”, in Science, volume 276, issue 5321, pages 2050-2054:

     A CRF antagonist, -helical CRF(9-41), can also attenuate the anxiogenic behavioral effects of HU-210.

   • 1997, August 8, Lester Grinspoon et al., “Marijuana Addiction”, in Science, volume 277, issue 5327, pages 749-753:

     Increases in dopamine efflux in the NAS cannot simply be seen as equivalent to drug reward, because aversive stimuli, such as foot shock, and anxiogenic drugs, such as FG 7142 and beta-CCE (which are not self-administered), have exactly the same neurochemical effect (3 ).

   • 1998 September 11, Mark S. Kramer et al., “Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors”, in Science, volume 281, issue 5383, pages 1640-1645:

     Central injection of substance P or related peptide agonists induces conditioned place aversion and produces an anxiogenic profile on the elevated plus maze, implying that activation of central substance P pathways is aversive (5 ).

   • 2000 July 28, Frans B. M. de Waal, “Primates--A Natural Heritage of Conflict Resolution”, in Science, volume 289, issue 5479, 586-590:

     Thus, self-directed behavior increases after anxiogenic drug treatment but decreases after anxiolytic drug treatment (29 ).

• anxiogenicity

• anxiogenesis

• (causing anxiety): anxiolytic

anxiogenic (plural anxiogenics)

1. An anxiogenic drug: a drug that causes anxiety.

• (anxiogenic drug): anxiolytic