[c. 1980s?] The state wherein a substance, having previously been reduced or removed, has or is being replaced by re-adding it, but overly so, resulting in more of the substance than normal.
1983, Michael Christopher Magee, Basic science for the practicing urologist, →ISBNInvalidISBN, page 63:
... liberal replacement or overreplacement with blood and plasma preoperatively and operatively has made obsolete the use of vasopressors, which in the past ...