unwholesome

From Middle English unholsom. Equivalent to un- +‎ wholesome.

unwholesome (comparative more unwholesome, superlative most unwholesome)

1. Not wholesome; unfavorable to health; unhealthful.

   unwholesome air, or food

   • 1610–1611, William Shakespeare, “The Tempest”, in Mr. William Shakespeares Comedies, Histories, & Tragedies: Published According to the True Originall Copies (First Folio), London: Printed by Isaac Iaggard, and Ed[ward] Blount, published 1623, OCLC 606515358, [Act I, scene ii], page 4:

     Caliban: As wicked dewe, as ere my mother bruſh'd / With Rauens feather from vnwholeſome Fen / Drop on you both : A Southweſt blow on yee, / And bliſter you all ore.

2. Not sound; tainted; defective.
3. Indicating unsound health; characteristic of or suggesting an unsound condition, physical or mental; repulsive; offensive.

• wholesome
• unwholesomely
• unwholesomeness

• unwholesome in The Century Dictionary, New York, N.Y.: The Century Co., 1911.