acromegaly

(noun)

A chronic disease marked by enlargement of the bones of the extremities, face, and jaw that is caused by over-activity of the pituitary gland.

Related Terms

Examples of acromegaly in the following topics:

  • Hormonal Abnormalities and Height

    • This expansion causes the headaches and visual disturbances that often accompany acromegaly.
    • When these non-pituitary tumors are surgically removed, GH levels fall and the symptoms of acromegaly improve.
    • If it occurs after the closure of the epiphyses (i.e., in adults), then acromegaly ensues.
    • Teeth showing classic teeth gapping due to acromegaly on the mandible.
    • This image depicts the facial aspect of a patient with acromegaly.

  • Pituitary Gland Disorders

    • The distinction between gigantism (occurring in children) and acromegaly (occurring in adults) can be made by the occurrence of the adenoma in relation to the closure of the epiphyses.
    • If it occurs after the closure of the epiphyses (i.e., in adults) then acromegaly ensues.

  • Hormonal Regulation of Growth

    • In adults, excessive GH can lead to acromegaly, a condition in which there is enlargement of bones in the face, hands, and feet that are still capable of growth.

  • Hypertension

    • Hypertension can also be caused by endocrine conditions, such as Cushing's syndrome, hyperthyroidism, hypothyroidism, and acromegaly.