Examples of cell wall in the following topics:
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Inhibiting Cell Wall Synthesis
- Two types of antimicrobial drugs work by inhibiting or interfering with cell wall synthesis of the target bacteria.
- Antibiotics commonly target bacterial cell wall formation (of which peptidoglycan is an important component) because animal cells do not have cell walls.
- The peptidoglycan layer is important for cell wall structural integrity, being the outermost and primary component of the wall.
- Diagram depicting the failure of bacterial cell division in the presence of a cell wall synthesis inhibitor (e.g. penicillin, vancomycin).1- Penicillin (or other cell wall synthesis inhibitor) is added to the growth medium with a dividing bacterium.2- The cell begins to grow, but is unable to synthesize new cell wall to accommodate the expanding cell.3- As cellular growth continues, cytoplasm covered by plasma membrane begins to squeeze out through the gap(s) in the cell wall.4- Cell wall integrity is further violated.
- The cell continues to increase in size, but is unable to "pinch off" the extra cytoplasmic material into two daughter cells because the formation of a division furrow depends on the ability to synthesize new cell wall.5- The cell wall is shed entirely, forming a spheroplast, which is extremely vulnerable relative to the original cell.
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Damage to the Cell Wall
- The cell wall is responsible for bacterial cell survival and protection against environmental factors and antimicrobial stress.
- While the peptidoglycan provides the structural framework of the cell wall, teichoic acids, which make up roughly 50% of the cell wall material, are thought to control the overall surface charge of the wall.
- Damage to the cell wall disturbs the state of cell electrolytes, which can activate death pathways (apoptosis or programmed cell death).
- A bacterial cell with a damaged cell wall cannot undergo binary fission and is thus certain to die .
- Discuss the effects that damage to the cell wall has on the bacterial cell
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Cell Walls of Archaea
- Archaeal cell walls differ from bacterial cell walls in their chemical composition and lack of peptidoglycans.
- Around the outside of nearly all archaeal cells is a cell wall, a semi-rigid layer that helps the cell maintain its shape and chemical equilibrium.
- For instance, the cell walls of all bacteria contain the chemical peptidoglycan.
- The cell wall of archaeans is chemically distinct.
- State the similarities between the cell walls of archaea and bacteria
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The Cell Wall of Bacteria
- Bacteria are protected by a rigid cell wall composed of peptidoglycans.
- Bacterial cells lack a membrane bound nucleus.
- A wall located outside the cell membrane provides the cell support, and protection against mechanical stress or damage from osmotic rupture and lysis .
- The major component of the bacterial cell wall is peptidoglycan or murein.
- The cell wall provides important ligands for adherence and receptor sites for viruses or antibiotics.
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Mycoplasmas and Other Cell-Wall-Deficient Bacteria
- Some bacteria lack a cell wall but retain their ability to survive by living inside another host cell.
- For most bacterial cells, the cell wall is critical to cell survival, yet there are some bacteria that do not have cell walls.
- Cell walls are unnecessary here because the cells only live in the controlled osmotic environment of other cells.
- It is likely they had the ability to form a cell wall at some point in the past, but as their lifestyle became one of existence inside other cells, they lost the ability to form walls.
- Other bacterial species occasionally mutate or respond to extreme nutritional conditions by forming cells lacking walls, termed L-forms.
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Basic Structures of Prokaryotic Cells
- Most prokaryotes have a cell wall outside the plasma membrane.
- The composition of their cell walls also differs from the eukaryotic cell walls found in plants (cellulose) or fungi and insects (chitin).
- Some bacteria have a capsule outside the cell wall.
- Lipoteichoic acids anchor the cell wall to the cell membrane.
- In gram-positive bacteria, lipoteichoic acid anchors the cell wall to the cell membrane.
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Virus Attachment and Genome Entry
- Instead, they use the machinery and metabolism of a host cell to produce multiple copies of themselves, and they assemble in the cell.
- This is often called "viral entry. " The infection of plant and fungal cells is different from that of animal cells.
- Plants have a rigid cell wall made of cellulose, and fungi one of chitin, so most viruses can get inside these cells only after trauma to the cell wall.
- Bacteria, such as plants, have strong cell walls that a virus must breach to infect the cell.
- However, given that bacterial cell walls are less thick than plant cell walls due to their much smaller size, some viruses have evolved mechanisms that inject their genome into the bacterial cell across the cell wall, while the viral capsid remains outside
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Comparing Plant and Animal Cells
- The cell wall is a rigid covering that protects the cell, provides structural support, and gives shape to the cell.
- Fungal and protistan cells also have cell walls.
- While the chief component of prokaryotic cell walls is peptidoglycan, the major organic molecule in the plant cell wall is cellulose , a polysaccharide comprised of glucose units.
- That's because you are tearing the rigid cell walls of the celery cells with your teeth.
- As the central vacuole shrinks, it leaves the cell wall unsupported.
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Intercellular Junctions
- In general, long stretches of the plasma membranes of neighboring plant cells cannot touch one another because they are separated by the cell wall that surrounds each cell.
- Plasmodesmata are numerous channels that pass between cell walls of adjacent plant cells and connect their cytoplasm; thereby, enabling materials to be transported from cell to cell, and thus throughout the plant .
- Also found only in animal cells are desmosomes, the second type of intercellular junctions in these cell types.
- A plasmodesma is a channel between the cell walls of two adjacent plant cells.
- Plasmodesmata allow materials to pass from the cytoplasm of one plant cell to the cytoplasm of an adjacent cell.
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Cells as the Basic Unit of Life
- Close your eyes and picture a brick wall.
- What is the basic building block of that wall?
- Like a brick wall, your body is composed of basic building blocks, and the building blocks of your body are cells.
- A living thing, whether made of one cell (like bacteria) or many cells (like a human), is called an organism.
- For example, both animal and plant cells are classified as eukaryotic cells, whereas bacterial cells are classified as prokaryotic.