Epstein-Barr virus (EBV)

(noun)

Virus responsible for causing infectious mononucelosis.

Related Terms

Examples of Epstein-Barr virus (EBV) in the following topics:

  • Infectious Mononucleosis

    • Mononucleosis is an infectious disease caused by the Epstein-Barr virus (EBV) and results in flu-like symptoms.
    • Infectious mononucleosis is an infectious, widespread viral disease caused by the Epstein–Barr virus (EBV), one type of herpes virus, to which more than 90% of adults have been exposed.
    • Most people are exposed to the virus as children, when the disease produces no noticeable or only flu-like symptoms.
    • But once infected, the patient carries the virus for the rest of his or her life.
    • The virus typically lives dormantly in B lymphocytes.

  • Other Diseases and Epstein-Barr Virus

    • Epstein-Barr virus (EBV) is a member of the herpesvirus family and is best known as the cause of infectious mononucleosis.
    • The Epstein–Barr virus (EBV), also called human herpesvirus 4 (HHV-4), is a virus of the herpes family, and is one of the most common viruses in humans.
    • In latency, only a portion of EBV's genes are expressed.
    • The EBV occurs all over the world and most people become infected with this virus at some point in their lives.
    • Distinguish between the lytic replicative and latency cycle of the Epstein-Barr virus infection cycle and discuss the prevalence of Epstein-Barr virus infected humans

  • Burkitt's Lymphoma

    • Children affected with the disease often also have chronic malaria, which is believed to have reduced resistance to Epstein-Barr virus (EBV), allowing it to take hold.
    • Again it is believed that impaired immunity provides an opening for development of the Epstein-Barr virus.

  • RNA Oncogenic Viruses

    • These viruses have varying ways of reproduction and represent several different virus families.
    • Human T lymphotrophic virus type 1 (HTLV-I), a retrovirus, has been linked to T-cell leukemia. 2.
    • The hepatitis C virus has been linked to liver cancer in people with chronic infections .
    • Epstein-Barr virus (EBV) has been linked to Burkitt's lymphoma, Hodgkin's lymphoma, post-transplantation lymphoproliferative disease, and nasopharyngeal carcinoma.
    • Thus, the virus is diploid.

  • Double-Stranded DNA Viruses: Herpesviruses

    • Varicella zoster virus (VZV) is one of eight herpes viruses known to infect humans and other vertebrates.
    • These genes encode a variety of proteins involved in forming the capsid, tegument and envelope of the virus, as well as controlling the replication and infectivity of the virus.
    • Infection is initiated when a viral particle comes in contact with the target cell specific to the individual herpes virus.
    • In this fashion, the virus can persist in the cell (and thus the host) indefinitely.
    • There are two strains of the herpes simplex virus, HSV-1, which is responsible for cold sores, and HSV-2, which is responsible for genital herpes.

  • Replication of Double-Stranded DNA Viruses of Animals

    • From the perspective of the virus, the purpose of viral replication is to allow production and survival of its kind.
    • Most of these viruses, such as BK virus and JC virus, are very common and typically asymptomatic in most human populations studied.
    • At this point viral gene expression can occur and new virus particles can be generated.
    • At least five species of Herpesviridae – HSV-1 and HSV-2 (both of which can cause orolabial herpes and genital herpes), Varicella zoster virus (which causes chicken-pox and shingles), Epstein-Barr virus (which causes mononucleosis), and Cytomegalovirus – are extremely widespread among humans.
    • In total, there are 8 herpesvirus types that infect humans: herpes simplex viruses 1 and 2, varicella-zoster virus, EBV (Epstein-Barr virus), human cytomegalovirus, human herpesvirus 6, human herpesvirus 7, and Kaposi's sarcoma-associated herpesvirus.

  • DNA Oncogenic Viruses

    • The Epstein-Barr virus has been linked to Burkitt's lymphoma.
    • This virus infects B cells of the immune system and epithelial cells.
    • Human herpes virus-8 has been linked to the development of Kaposi sarcoma.
    • These are the early control functions of the virus.
    • The first DNA tumor viruses to be discovered were rabbit fibroma virus and Shope papilloma virus, both discovered by Richard Shope in the 1930s.

  • Virus Classification

    • However, these earlier classification methods grouped viruses based on which features of the virus they were using to classify them.
    • The virus core contains the genome or total genetic content of the virus.
    • For example, the tobacco mosaic virus has a naked helical capsid .
    • (a) Rabies virus has a single-stranded RNA (ssRNA) core and an enveloped helical capsid, whereas (b) variola virus, the causative agent of smallpox, has a double-stranded DNA (dsDNA) core and a complex capsid.
    • The capsid of the (a) polio virus is naked icosahedral; (b) the Epstein-Barr virus capsid is enveloped icosahedral; (c) the mumps virus capsid is an enveloped helix; (d) the tobacco mosaic virus capsid is naked helical; and (e) the herpesvirus capsid is complex.

  • Genital Herpes

    • Herpes genitalis (or genital herpes) refers to a genital infection by Herpes simplex virus.
    • Herpes genitalis (or genital herpes) refers to a genital infection by Herpes simplex virus .
    • Among these drugs are: acyclovir, valacyclovir and famciclovir.Acyclovir is an antiviral drug used against herpes viruses, varicella-zoster, and Epstein-Barr Viruses.
    • The ointment is used topically and it decreases pain, reduces healing time, and limits the spread of the infection.Valacyclovir is also used to treat herpes virus infections.
    • Recognize the causes and symptoms of herpes simplex virus (HSV) 1 and 2

  • Diagnostic Blood Tests

    • It is generally diagnosed with a blood test that is analyzed for the presence of antibodies to the Epstein-Barr virus.