estradiol
Physiology
Biology
Examples of estradiol in the following topics:
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Puberty
- While testosterone produces all boys' changes characterized as virilization, a substantial product of testosterone metabolism in males is estradiol.
- The conversion of testosterone to estradiol depends on the amount of body fat and estradiol levels in boys are typically much lower than in girls.
- The hormone that dominates female development is an estrogen called estradiol.
- While estradiol promotes growth of breasts and uterus, it is also the principal hormone driving the pubertal growth spurt and epiphyseal maturation and closure.
- Estradiol levels rise earlier and reach higher levels in women than in men.
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Aging and the Endocrine System
- Three hormone axes are affected by aging: growth hormone/insulin-like growth factor I, cortisol/dehydroepiandrosterone, and testoterone/estradiol.
- Three of the most important hormone axes in the endocrine system that are affected by aging include growth hormone (GH)/insulin-like growth factor I (IGF-I), cortisol/dehydroepiandrosterone (DHEA), and testosterone/estradiol.
- Menopause/andropause refers to the decrease in production and circulation of estradiol (estrogen) in females and testosterone in males.
- Estradiol is the female equivalent of testosterone and is secreted from granulosa cells.
- Evaluate the effects of the hormonal axes affected by aging [growth hormone (GH)/insulin-like growth factor I (IGF-I), cortisol/dehydroepiandrosterone (DHEA), and testosterone/estradiol]
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Hormonal Regulation of the Male Reproductive System
- They are capable of producing the hormones estradiol and inhibin.
- The Leydig cells are also capable of producing estradiol in addition to their main product, testosterone.
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Hormonal Regulation of the Reproductive System
- LH also plays a role in the development of ova, induction of ovulation, and stimulation of estradiol and progesterone production by the ovaries .
- Estradiol and progesterone are steroid hormones that prepare the body for pregnancy.
- Estradiol produces secondary sex characteristics in females, while both estradiol and progesterone regulate the menstrual cycle.
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Lipid-Derived, Amino Acid-Derived, and Peptide Hormones
- Examples of steroid hormones include estradiol, which is an estrogen, or female sex hormone, and testosterone, which is an androgen, or male sex hormone.
- The structures shown here represent (a) cholesterol, plus the steroid hormones (b) testosterone and (c) estradiol.
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Female Hormones
- LH also plays a role in the development of ova, as well as in the induction of ovulation and stimulation of estradiol and progesterone production by the ovaries.
- Estradiol and progesterone are steroid hormones that prepare the body for pregnancy.
- Estradiol is the reproductive hormone in females that assists in endometrial regrowth, ovulation, and calcium absorption; it is also responsible for the secondary sexual characteristics of females.
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Intramuscular Injections
- Compunds and drugs that are administered via IM injection include: Codeine, Morphine, Methotrexate, Metoclopramide, Olanzapine, Streptomycin, Diazepam, Prednisone, Penicillin, Interferon beta-1a, Sex hormones, such as Testosterone, Estradiol Valerate, and Depo Provera Dimercaprol, Ketamine, Lupron, Naloxone, and Quinine, in its gluconate form Vitamin B12, also known as cyanocobalamin.
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Administering Hormones
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Menopause
- Menopause is based on the natural or surgical cessation of estradiol and progesterone production by the ovaries, which are a part of the body's endocrine system of hormone production, in this case the hormones which make reproduction possible and influence sexual behavior.
- However the dramatic fall in circulating estradiol levels at menopause impacts many tissues, from brain to skin.
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Extrauterine Effects of Estrogens and Progesterone
- The three major naturally occurring forms of estrogen in women are estrone (E1), estradiol (E2), and estriol (E3).