Examples of gastrin in the following topics:
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- Gastric secretion is stimulated chiefly by three chemicals: acetylcholine (ACh), histamine, and gastrin.
- Gastrin is a hormone produced by enteroendocrine G cells in the pyloric glands.
- The chief cells secrete pepsinogen in response to gastrin and especially Ach, and ACh also stimulates mucus secretion.
- As dietary protein is digested, it breaks down into smaller peptides and amino acids, which directly stimulate the G cells to secrete even more gastrin: a positive feedback loop that accelerates protein digestion.
- During the gastric phase, gastrin is secreted.
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- The hormone gastrin causes an increase in the secretion of HCl from the parietal cells, and pepsinogen from chief cells in the stomach.
- Other than gastrin, these hormones all act to turn off the stomach's action.
- The pyloric gland, found in the stomach, secretes gastrin and other hormones.
- The cardiac gland, found in the stomach, secretes gastrin and other hormones.
- The fundic gland, found in the stomach, secretes gastrin and other hormones.
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- Stretching of the duodenum accentuates vagal reflexes that stimulate the stomach, and peptides and amino acids in the chyme stimulate G cells of the duodenum to secrete more gastrin, which further stimulates the stomach.
- The effect of this is that gastrin secretion declines and the pyloric sphincter contracts tightly to limit the admission of more chyme into the duodenum.
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- Gastrin is in the stomach and stimulates the gastric glands to secrete pepsinogen (an inactive form of the enzyme pepsin) and hydrochloric acid.
- Secretion of gastrin is stimulated by food arriving in the stomach.
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- There will also be an influence on G cells to increase gastrin circulation.
- Chemical stimuli (i.e., partially digested proteins, caffeine) directly activate G-cells (enteroendocrine cells) located in the pyloric region of the stomach to secrete gastrin; this in turn stimulates gastric glands to secrete gastric juice.
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- When this reflex is stimulated, the release of gastrin from G-cells in the antrum of the stomach is shut off.
- These hormones fall into three major categories: the gastrin family, the secretin family, and a third family composed of the remaining hormones that fit into neither of the these two families.
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- During the gastric phase, the hormone gastrin is secreted by G cells in the stomach in response to the presence of proteins.
- Gastrin stimulates the release of stomach acid, or hydrochloric acid (HCl), which aids in the digestion of the majority of proteins.
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- Gastrin - is in the stomach and stimulates the gastric glands to secrete pepsinogen (an inactive form of the enzyme pepsin) and hydrochloric acid.
- Secretion of gastrin is stimulated by food arriving in stomach.
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- Thus, the bacterium can cause a chronic active gastritis, resulting in a defect in the regulation of gastrin production by that part of the stomach.
- Gastrin secretion can either be increased, or as in most cases, decreased, resulting in a too basic or too acidic stomach environment, respectively.
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- Zollinger-Ellison syndrome, which can be present with increased gastric acidity due to gastrin production.