7-dehydrocholesterol

Examples of 7-dehydrocholesterol in the following topics:

• Metabolic Functions

  • One of the metabolic functions of the skin is the production of vitamin D3 when ultraviolet light reacts with 7-dehydrocholesterol.
  • Vitamin D3 is made in the skin when the 7-dehydrocholesterol reacts with ultraviolet light of UVB type at wavelengths between 280 and 315 nm, with peak synthesis occurring between 295 and 297 nm.

• Alkalosis

  • Alkalosis is the increased alkalinity of blood and other tissues, generally occurring when the blood pH is above 7.45.
  • Generally, alkalosis is said to occur when pH of the blood exceeds 7.45.
  • The opposite condition is acidosis (when pH falls below 7.35).
  • Metabolic alkalosis is a metabolic condition in which the pH of tissue is elevated beyond the normal range (7.35-7.45 ).

• Disorders of Acid-Base Balance

  • Acid–base imbalance is an abnormality of the human body's normal balance of acids and bases that causes the plasma pH to deviate out of normal range (7.35 to 7.45) .
  • In the fetus, the normal range differs based on which umbilical vessel is sampled (umbilical vein pH is normally 7.25 to 7.45; umbilical artery pH is normally 7.18 to 7.38).
  • If unchecked, metabolic acidosis leads to acidemia, i.e., blood pH is low (less than 7.35) due to increased production of hydrogen by the body or the inability of the body to form bicarbonate (HCO3-) in the kidneys.
  • Metabolic alkalosis is a metabolic condition in which the pH of tissue is elevated beyond the normal range (7.35-7.45 ).

• Chemical Composition of Bone

  • Acid-base imbalance is an abnormality of the human body's normal balance of acids and bases that causes the plasma pH to deviate out of normal range (7.35 to 7.45) .
  • In the fetus, the normal range differs based on which umbilical vessel is sampled (umbilical vein pH is normally 7.25 to 7.45; umbilical artery pH is normally 7.18 to 7.38).
  • If unchecked, metabolic acidosis leads to acidemia, that is, blood pH is less than 7.35 due to increased production of hydrogen by the body, or because of the body's inability to form bicarbonate (HCO3-) in the kidneys.
  • Metabolic alkalosis is a metabolic condition in which the pH of tissue is elevated beyond the normal range (7.35 to 7.45).

• Acidosis

  • Acidosis describes increased acidity in the blood and other tissues, usually measured as arterial pH below 7.35.
  • Acidosis is said to occur when arterial pH falls below 7.35, while its counterpart (alkalosis) occurs at a pH over 7.45.
  • In humans, the normal pH of arterial blood lies between 7.35 and 7.45.
  • Blood pH values compatible with life in all mammals are limited to a pH range between 6.8 and 7.8.

• Chemical Buffer Systems

  • The body's acid–base balance is normally tightly regulated, keeping the arterial blood pH between 7.38 and 7.42.

• Potassium Balance Regulation

  • A high pH (ie. alkalosis >7.4) favors movement of K+ into the cells whilst a low pH (ie. acidosis) causes movement out of the cell.
  • Therefore, a person with an acidosis (pH 7.1) and a plasma K+ of 6.5 mmol/l could be depleted of total body potassium.

• The Role of the Kidneys in Acid-Base Balance

  • Within the human body, fluids such as blood must be maintained within the narrow range of 7.35 to 7.45, making it slightly alkaline.

• Regulation of H+ by the Lungs

  • Acid–base imbalance occurs when a significant insult causes the blood pH to shift out of the normal range (7.35 to 7.45).

• The Gallbladder

  • It is about 7–10cm long in humans and is dark green in color.