Concept
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Cholinergic Neurons and Receptors
Nicotinic acetylcholine receptors
These schematics describe the heteromeric and homomeric nature of nAChRs. The heteromeric receptors found in the central nervous system are made up of 2 α and 3 β subunits with the binding site at the interface of α and adjacent subunit. Homomeric receptors contain 5 identical subunits and have 5 binding sites located at the interfaces between adjacent subunits.
These schematics describe the heteromeric and homomeric nature of nAChRs. The heteromeric receptors found in the central nervous system are made up of 2 α and 3 β subunits with the binding site at the interface of α and adjacent subunit. Homomeric receptors contain 5 identical subunits and have 5 binding sites located at the interfaces between adjacent subunits.
Source
Boundless vets and curates high-quality, openly licensed content from around the Internet. This particular resource used the following sources:
"Drug Discovery and Development: Nicotinic Acetylcholine Receptor Agonists."
http://en.wikipedia.org/wiki/Drug_Discovery_and_Development:_Nicotinic_Acetylcholine_Receptor_Agonists
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