Examples of macrophage in the following topics:
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- A macrophage is a large, phagocytic cell that engulfs foreign particles and pathogens.
- Macrophages recognize PAMPs via complementary pattern recognition receptors (PRRs).
- Both macrophages and dendritic cells engulf pathogens and cellular debris through phagocytosis.
- Monocytes mature into macrophages.
- Neutrophils and macrophages also consume invading bacteria by phagocytosis.
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- Approximately 0.1 percent of all cells in the blood are leukocytes, which include monocytes (the precursor of macrophages) and lymphocytes.
- Lymph nodes scattered throughout the body house large populations of T and B cells, dendritic cells, and macrophages .
- The spleen houses B and T cells, macrophages, dendritic cells, and NK cells .
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- Some white blood cells become macrophages that either stay at the same site or move through the blood stream and gather at sites of infection or inflammation where they are attracted by chemical signals from foreign particles and damaged cells.
- After the HIV virus replicates, it is transmitted directly from the infected T cell to macrophages.
- Monocytes differentiate into macrophages and dendritic cells, which in turn respond to infection or injury.
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- A good example of this occurs in a group of white blood cells called macrophages, which are part of your body's immune system.
- In a process known as phagocytosis or endocytosis, a section of the plasma membrane of the macrophage invaginates (folds in) and engulfs a pathogen.
- A macrophage has engulfed (phagocytized) a potentially pathogenic bacterium and then fuses with a lysosomes within the cell to destroy the pathogen.
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- Cells of the liver and macrophages synthesize complement proteins continuously.
- They serve as a marker to indicate the presence of a pathogen to phagocytic cells, such as macrophages and B cells, to enhance engulfment.
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- First, an antigen-presenting cell (APC, such as a dendritic cell or a macrophage) detects, engulfs (via phagocytosis in the case of macrophages or by entry of the pathogen of its own accord in the case of dendritic cells), and digests pathogens into hundreds or thousands of antigen fragments.
- Cytokines are signaling molecules secreted by a TH cell in response to a pathogen-infected cell; they stimulate natural killer cells and phagocytes such as macrophages.
- An antigen-presenting cell (APC), such as a macrophage, engulfs a foreign antigen, partially digests it in a lysosome, and then embeds it in an MHC class II molecule for presentation at the cell surface.
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- The cell responsible for bone resorption, or breakdown, is the osteoclast, which is found on bone surfaces, is multinucleated, and originates from monocytes and macrophages (two types of white blood cells) rather than from osteogenic cells.
- Osteoclasts develop from monocytes and macrophages and differ in appearance from other bone cells.
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- Antibodies also opsonize pathogen cells, wherein they mark them for destruction by phagocytic cells, such as macrophages or neutrophils.
- Antibodies may inhibit infection by (a) preventing the antigen from binding its target, (b) tagging a pathogen for destruction by macrophages or neutrophils, or (c) activating the complement cascade.
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- Antibodies also mark pathogens for destruction by phagocytic cells, such as macrophages or neutrophils, because they are highly attracted to macromolecules complexed with antibodies.
- Antibodies may inhibit infection by (a) preventing the antigen from binding to its target, (b) tagging a pathogen for destruction by macrophages or neutrophils, or (c) activating the complement cascade.
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- Macrophages, lymphocytes, and, occasionally, leukocytes can be found in some of the tissues, while others may have specialized cells.
- Loose connective tissue has some fibroblasts, although macrophages are present as well.