chondroblast

Examples of chondroblast in the following topics:

• Cartilage Growth

  • Mesenchyme tissue differentiates into chondroblasts and begins secreting the molecules that form the extracellular matrix (ECM).
  • These condrogenic cells then differentiate to chondroblasts, which will then synthesize the cartilage ECM.
  • The chondroblasts then trap themselves in lacunae, small spaces that are no longer in contact with the newly created matrix and contain extracellular fluid.
  • The chondroblast is now a chondrocyte, which is usually inactive but can still secrete and degrade the matrix depending on the conditions.
  • The majority of body cartilage is synthesized from chondroblasts that are largely inactive at later developmental stages compared to earlier years (pre-pubescence).

• Bone Repair

  • The periosteum is one source of precursor cells that develop into the chondroblasts and osteoblasts that are essential to heal bone.
  • The periosteal cells proximal (closest) to the fracture gap develop into chondroblasts that form hyaline cartilage.
  • The fibroblasts within the granulation tissue develop into chondroblasts that also form hyaline cartilage.
  • However, if the bone is not set or improperly set, the chondroblasts and osteoblasts will still try to heal the bone but will be unable to return the bone to full proper functioning.

• Development of Joints

  • Chondrification (also known as chondrogenesis) is the process by which cartilage is formed from condensed mesenchyme tissue, which differentiates into chondroblasts and begins secreting the molecules that form the extracellular matrix.

• Types of Connective Tissue

  • Cartilage is composed of specialized cells called chondroblasts and, unlike other connective tissues, cartilage does not contain blood vessels.

• Structure, Type, and Location of Cartilage

  • Chondrocytes are first chondroblast cells that produce the collagen extracellular matrix (ECM) and then get caught in the matrix.