neutralization reaction
(noun)
a reaction between an acid and a base in which water and a salt are formed
Examples of neutralization reaction in the following topics:
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Neutralization Reaction
- Neutralization reactions are used to inactivate viruses and evaluate neutralizing antibodies.
- A neutralizing antibody defends a cell from an antigen or infectious body by inhibiting or neutralizing any effect it has biologically .
- Antibodies can also neutralize viral infectivity by binding to cell surface receptors.
- Neutralizing antibodies have shown potential in the treatment of retroviral infections.
- In diagnostic immunology and virology laboratories, the evaluation of neutralizing antibodies, which destroy the infectivity of viruses, can be measured by the neutralization method.
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Lewis Acid and Base Molecules
- The "neutralization" reaction is one in which a covalent bond forms between an electron-rich species (the Lewis base) and an electron-poor species (the Lewis acid).
- For now however, we will consider how the Lewis definition applies to classic acid-base neutralization.
- We have previously described this as an acid-base neutralization reaction in which water and a salt are formed.
- When considering Lewis acids and bases, the only real reaction of interest is the net ionic reaction:
- Thus, in this version of the neutralization reaction, what interests us is not the salt that forms, but the covalent bond that forms between OH- and H+ to form water.
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Strong Acid-Strong Base Titrations
- Using the stoichiometry of the reaction, the unknown concentration can be determined.
- It makes use of the neutralization reaction that occurs between acids and bases and the knowledge of how acids and bases will react if their formulas are known.
- The other reactant of known concentration remains in a burette to be delivered during the reaction.
- Neutralization is the reaction between an acid and a base, producing a salt and neutralized base.
- Neutralization is the basis of titration.
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Peroxisomes
- Peroxisomes neutralize harmful toxins and carry out lipid metabolism and oxidation reactions that break down fatty acids and amino acids.
- They also carry out oxidation reactions that break down fatty acids and amino acids.
- In this way, peroxisomes neutralize poisons, such as alcohol, that enter the body.
- Peroxisomes oversee reactions that neutralize free radicals.
- Like miniature sewage treatment plants, peroxisomes neutralize harmful toxins so that they do not cause damage in the cells.
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Reactions of Epoxides
- Epoxides (oxiranes) are three-membered cyclic ethers that are easily prepared from alkenes by reaction with peracids.
- The aqueous acid used to work up the third reaction, following the Grignard reagent cleavage of the ethylene oxide, simply neutralizes the magnesium salt of the alcohol product.
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Important Reagent Bases
- The common base sodium hydroxide is not soluble in many organic solvents, and is therefore not widely used as a reagent in organic reactions.
- Pyridine is commonly used as an acid scavenger in reactions that produce mineral acid co-products.
- Hünig's base is relatively non-nucleophilic (due to steric hindrance), and like DBU is often used as the base in E2 elimination reactions conducted in non-polar solvents.
- Barton's base is a strong, poorly-nucleophilic, neutral base that serves in cases where electrophilic substitution of DBU or other amine bases is a problem.
- An interesting group of neutral, highly basic compounds of nitrogen and phosphorus have been prepared, and are referred to as superbases.
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Electrolytic Properties
- The ions in the electrolyte neutralize these charges, enabling the electrons to keep flowing and the reactions to continue.
- The positively-charged sodium ions Na+ will react toward the cathode, neutralizing the negative charge of OH− there; the negatively-charged hydroxide ions OH− will react toward the anode, neutralizing the positive charge of Na+ there.
- Oxidation of ions or neutral molecules occurs at the anode, and the reduction of ions or neutral molecules occurs at the cathode.
- Neutral molecules can also react at either electrode.
- Recall that a more positive potential always means that that reaction will be favored; this will have consequences concerning redox reactions.
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The Arndt-Eistert Reaction
- If the HCl is not neutralized by a base, this mixture reacts further to give a chloromethyl ketone with loss of nitrogen.
- However, if the HCl is neutralized as it is formed, the relatively stable diazo ketone is obtained and may be used in subsequent reactions.
- One equivalent of diazomethane is required for this reaction.
- The first two examples are typical Arndt-Eistert reactions.
- Reaction #3 is an example of such an alternative reaction.
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Types of Redox Reactions
- Redox reactions are all around us.
- Redox reactions are matched sets: if one species is oxidized in a reaction, another must be reduced.
- In this equation, the water is "decomposed" into hydrogen and oxygen, both of which are neutral.
- Displacement reactions, also known as replacement reactions, involve compounds and the "replacing" of elements.
- Oxygen has been both oxidized and reduced in the reaction, making this a disproportionation reaction.
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Enzyme Active Site and Substrate Specificity
- In some reactions, a single-reactant substrate is broken down into multiple products.
- Two reactants might also enter a reaction, both become modified, and leave the reaction as two products.
- Each amino acid residue can be large or small; weakly acidic or basic; hydrophilic or hydrophobic; and positively-charged, negatively-charged, or neutral.
- This dynamic binding maximizes the enzyme's ability to catalyze its reaction.
- After an enzyme is done catalyzing a reaction, it releases its products (substrates).