septic shock
(noun)
A life-threatening condition caused by infection and sepsis, often after surgery or trauma.
Examples of septic shock in the following topics:
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Sepsis and Septic Shock
- Frequently, patients suffering from septic shock are cared for in intensive care units.
- The mortality rate from septic shock is approximately 25–50%.
- In sepsis, blood pressure drops, resulting in septic shock.
- There are new drugs that act against the extreme inflammatory response seen in septic shock.
- Compare and contrast the symptoms of: sepsis, severe sepsis, septic shock
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Pyelonephritis
- Pyelonephritis that has progressed to urosepsis may be accompanied by signs of septic shock, including rapid breathing, decreased blood pressure, violent shivering, and occasionally delirium.
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Signs and Symptoms of Shock
- The clinical manifestation of shock varies depending on the type of shock and the individual, but there are some general symptoms.
- The presentation of shock varies.
- The symptoms of cardiogenic shock are similar to those of hypovolemic shock.
- Distributive shock includes septic, anaphylactic, and neurogenic causes.
- With septic shock, fever may occur and the skin may be warm and sweaty.
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Types of Shock
- Circulatory shock, commonly known simply as shock, is a life-threatening medical condition that occurs due to inadequate substrates for aerobic cellular respiration.
- In some people with circulatory shock, blood pressure remains stable.
- Specific subtypes of shock may have additional symptoms.
- Distributive shock is caused by an abnormal distribution of blood to tissues and organs and includes septic, anaphylactic, and neurogenic causes.
- Septic shock is the most common cause of distributive shock and is caused by an overwhelming systemic infection that cannot be cleared by the immune system, resulting in vasodilation and hypotension.
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Fever
- For example, septic shock is a severe bacterial infection in which bacterial toxins stimulate pyrogen and inflammatory mediator activity causes high fever.
- The fever makes it harder for the body to stop the systemic organ failure that occurs from the compensatory mechanisms in septic shock.
- While septic shock is one of the worst possible examples of fever, it illustrates an important concept in pathophysiology: that normal immune functions are as easily able to hurt us as help us..
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Salmonellosis
- In the generalized form of the disease, salmonellae pass through the lymphatic system of the intestine into the blood of the patients (typhoid form) and are carried to various organs (liver, spleen, kidneys) to form secondary foci (septic form).
- In severe forms of the disease, enough liquid and electrolytes are lost to upset the body's metabolism of water and salt, decreasing the circulating blood volume and arterial pressure to enough of a degree to cause hypovolemic shock.
- Septic shock may also develop.
- Shock of mixed character (with signs of both hypovolemic and septic shock) is more common in severe salmonellosis.
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Noncholera Vibrios
- Medical therapy consists of the following: prompt initiation of effective antibiotic therapy (doxycycline or a quinolone), intensive medical therapy with aggressive fluid replacement, vasopressors for hypotension and septic shock, early fasciotomy within 24 hours after development of clinical symptoms in patients with necrotizing fasciitis, early debridement of the infected wound, expeditious and serial surgical evaluation and intervention to prevent rapid deterioration, especially in patients with necrotizing fasciitis or compartment syndrome.
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Typing and Cross-Matching for Transfusions
- This can cause shock-like symptoms, such as fever, hypotension, and disseminated intravascular coagulation from immune system mediated endothelial damage.
- If the donated blood is contaminated with bacteria, it may induce septic shock in the patient.
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Breathing Patterns
- It is a symptom of exercise and adjustment to high altitude, which are generally not problematic, but can also be seen in those with anemia or septic shock, which is problematic.
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Water Balance Disorders
- Hypovolemia is a cause of hypovolemic shock.
- Shock is any condition in which the body's fluids are unable to properly circulate and oxygenate the major organs of the human body, causing compensatory mechanisms to activate, which cause further bodily harm as the body's metabolism is maintained for a while longer.
- In the case of hypovolemic shock, tissue metabolism is impaired due to a lack of blood volume, making it difficult for red blood cells to reach all of the tissues of the body.
- Other forms of shock with similar symptoms may be due to problems in the heart (cardiogenic) or bacterial infection (septic).