von Willebrand Factor

Examples of von Willebrand Factor in the following topics:

• Hemostasis Disorders

  • The most common blood disorders, Von Willebrand disease, hemophilia, and Factor V Leiden thrombophilia, all involve defects in the amount or activity of factors involved in coagulation.
  • Those affected by von Willebrand disease will have low levels of von Willebrand factor, a protein that helps the blood to clot, and/or their von Willebrand factor does not work properly.
  • In this type of disease, there is a low level of von Willebrand factor.
  • In this type of disease, there is a defect in von Willebrand factor resulting in improper activity.
  • In this type of disease, individuals usually do not produce von Willebrand factor and have very low levels of factor VIII.

• Overview of Hemostasis

  • When endothelial injury occurs, the endothelial cells stop secretion of coagulation and aggregation inhibitors and instead secrete von Willebrand factor, which causes platelet adherence during the initial formation of a clot.
  • Von Willebrand factor causes them to adhere to each other and the walls of the vessel.
  • At least 12 substances called clotting factors or tissue factors take part in a cascade of chemical reactions that eventually create a mesh of fibrin within the blood.
  • Each of the clotting factors has a very specific function.
  • Prothrombin, thrombin, and fibrinogen are the main factors involved in the outcome of the coagulation cascade.

• Platelet Plug Formation

  • During an injury, subendothelial collagen from the extracellular matrix beneath the endothelial cells is exposed on the epithelium as the normal epithelial cells are damaged and removed, which releases von Willebrand Factor (VWF).
  • The released chemicals include ADP, VWF, thromboxane A2, platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), serotonin, and coagulation factors.
  • The other factors released during platelet activation perform other important functions.
  • The coagulation factors include factor V and VIII, which are involved in the coagulation cascade that converts fibrinogen into fibrin mesh after platelet plug formation.

• Entrepreneurship and the Economy

  • The accumulation of factors of production per se does not explain economic development.
  • The article was a prod to the economics profession to attend to this neglected factor.
  • Entrepreneurship is a factor in microeconomics, and its study reaches back to the work of Richard Cantillon and Adam Smith in the late 17th and early 18th centuries.
  • In the 20th century, the understanding of entrepreneurship owes much to the work of Joseph Schumpeter in the 1930s and other Austrian economists such as Carl Menger, Ludwig von Mises and Friedrich von Hayek.
  • Identify the characteristics of an entrepreneurial economy and the factors that lead to it

• Specific Heat for an Ideal Gas at Constant Pressure and Volume

  • It is sometimes also known as the isentropic expansion factor:
  • Julius Robert von Mayer (November 25, 1814 – March 20, 1878), a German physician and physicist, was one of the founders of thermodynamics.
  • His achievements were overlooked and credit for the discovery of the mechanical equivalent of heat was attributed to James Joule in the following year. von Mayer also proposed that plants convert light into chemical energy.

• The Taxonomic Scheme

  • In the scientific classification established by Carl von Linné, each distinct species is assigned to a genus using a two-part binary name (for example, Homo sapiens).
  • Outline the factors that play a role in the classification of bacterial taxonomy

• The Correction Factor

  • For risk neutral agents, the choice involves using the expected values of uncertain quantities, while for risk averse agents it involves maximizing the expected value of some objective function such as a von Neumann-Morgenstern utility function.

• Neutral Rights and Submarines

  • "England wants to starve us," said Admiral Alfred von Tirpitz, the man who built the German fleet and who remained a key adviser to the Kaiser Wilhelm II.
  • They believed that the United States was so weak militarily that it could not be a factor on the Western Front for more than a year.

• Economic Way of Thinking

  • Much of Classical economics was macroeconomics in its concern about economic growth and the division of income among the various factors of production (land, labor, and capital.
  • Entrepreneurial ability as a factor was identified by Richard Cantillon [1680-1734] and popularized by J.B.
  • The Classical economists tended to focus on the functional distribution of income (The functional distribution refers to the distribution of income to the factors of production, land, labor and capital.
  • Johann Heinrich von Thünen [1783-1850, German] was one of the early writers who began to apply mathematical methods in the economics of location theory and wages.
  • Carl Menger and a group of followers (such as Eugen von Böhm-Bawerk [1851-1914], Friedrich von Wieser [1851-1926], Ludwig von Mises [1881-1973] and Friedrich Hayek [1899-1992]) have developed an alternative view of microeconomic behavior.

• Memory Distortions and Biases

  • Also, the same three factors that play a critical role in correct recall (i.e., recency, temporal association, and semantic relatedness) play a role in intrusions as well.
  • This effect, also known as the Von Restorff effect, is when an item that sticks out more (i.e., is noticeably different from its surroundings) is more likely to be remembered than other items.