transcriptome

(noun)

The complete set of messenger RNA molecules (transcripts) produced in a cell or a population of cells.

Related Terms

Examples of transcriptome in the following topics:

  • Microarrays and the Transciptome

    • The transcriptome is the set of all RNA molecules, including mRNA, rRNA, tRNA, and other non-coding RNA produced in cells.
    • The transcriptome is the set of all RNA molecules, including mRNA, rRNA, tRNA, and other non-coding RNA produced in one or a population of cells.
    • Unlike the genome, which is roughly fixed for a given cell line (excluding mutations), the transcriptome can vary with external environmental conditions.
    • A number of organism-specific transcriptome databases have been constructed and annotated to aid in the identification of genes that are differentially expressed in distinct cell populations.
    • The transcriptomes of stem cells and cancer cells are of particular interest to researchers who seek to understand the processes of cellular differentiation and carcinogenesis.

  • Metabolomics

    • One of the challenges of systems biology and functional genomics is to integrate proteomic, transcriptomic, and metabolomic information to give a more complete picture of living organisms.
    • The word was coined in analogy with transcriptomics and proteomics.
    • Like the transcriptome and the proteome, the metabolome is dynamic, changing from second to second.

  • Proteomics

    • After genomics and transcriptomics, proteomics is considered the next step in the study of biological systems.