National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Brugada syndrome



What is the prognosis for individuals diagnosed with Brugada syndrome?

The long-term outlook (prognosis) for people with Brugada syndrome varies because the condition is very unpredictable. The condition manifests primarily during adulthood, and causes a high risk of ventricular arrhythmias and sudden death. The average age of sudden death is approximately 40 years.[1][2] Affected people with a history of sudden cardiac arrest and/or fainting have an increased risk for subsequent episodes compared to people with no symptoms.[3]
Last updated: 3/16/2016

We hope this information is helpful. We strongly recommend you discuss this information with your doctor. If you still have questions, please contact us.

Warm regards,
GARD Information Specialist

Please see our Disclaimer.


  1. Brugada syndrome. Genetics Home Reference. March, 2015; http://ghr.nlm.nih.gov/condition=brugadasyndrome.
  2. Ramon Brugada, Oscar Campuzano, Pedro Brugada, Josep Brugada, and Kui Hong. Brugada Syndrome. GeneReviews. April 10, 2014; http://www.ncbi.nlm.nih.gov/books/NBK1517/.
  3. John V Wylie and Ann C Garlitski. Brugada syndrome. UpToDate. Waltham, MA: UpToDate; February, 2016;