National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Collagenous gastritis

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Does the condition eventually go away?
The course and long-term outlook (prognosis) for people with collagenous gastritis (CG) is unclear. There has not yet been a comprehensive review of outcomes, and large variations in the course of the disease have been reported.[1][2]

In the majority of adults, the condition seems to follow a chronic, intermittent course, with no significant mortality risk or severe progression. Diarrhea may resolve with or without treatment, although relapses may occur.[3] In children, a less controllable course has been suspected.[3] However, CG in children seems to follow a generally benign course, with limited long-term morbidity and no increased mortality reported to date.[1] A few reports have documented that the abnormal collagen band in affected people persists (with or without medication) despite symptoms improving.[3]
Last updated: 4/28/2015

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  1. Hijaz NM, Septer SS, Degaetano J, Attard TM. Clinical outcome of pediatric collagenous gastritis: case series and review of literature. World J Gastroenterol. March 7, 2013; 19(9):1478-1484. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602509/.
  2. Ma C, et. al. A Comparative Clinicopathologic Study of Collagenous Gastritis in Children and Adults: The Same Disorder With Associated Immune-mediated Diseases. Am J Surg Pathol. 2015 Jun; 39(6):802-12. https://www.ncbi.nlm.nih.gov/pubmed/?term=25871617.
  3. Rohan Mandaliya, Anthony J. DiMarino, Sheeja Abraham, Ashlie Burkart, Sidney Cohen. Collagenous Gastritis a Rare Disorder in Search of a Disease. Gastroenterology Research. 2013; 6(4):139-144. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5074812/.