National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Genuine diffuse phlebectasia


Other Names:
Bockenheimer syndrome
Categories:
Genuine diffuse phlebectasia or Bockenheimer's syndrome is a very rare condition characterized by an extensive venous malformation involving all veins, including the smallest ones, on the arms and legs. It is present at birth (congenital) and is progressive during life.[1][2]  The venous dilatation can be seen beneath the skin on the arms and legs. It is more common on a single arm and hand but may occur on both sides. The involved arm or leg may be thicker than the normal one.[1] Pain, swelling, muscle wasting, and ulceration can occur.[1][2] The cause is unknown.  Treatment may include surgery, embolization, and elastic stockings.[1]
Last updated: 7/1/2016

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  1. Osawa R, Kato N, Yanagi T & Yamane N. A case of Bockenheimer's syndrome (genuine diffuse phlebectasia): venous involvement inside muscles was detected by magnetic resonance imaging. Clin Exp Dermatol. November, 2007; 32(6):664-71. https://www.ncbi.nlm.nih.gov/pubmed/17953636.
  2. Kubiena, H. F., Liang, M. G. and Mulliken, J. B. Genuine Diffuse Phlebectasia of Bockenheimer: Dissection of an Eponym. Pediatric Dermatology. 2006; 23:294–297. https://www.ncbi.nlm.nih.gov/pubmed/16780484.