National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Epidermolytic palmoplantar keratoderma



Other Names:
Diffuse erythrodermic palmoplantar keratoderma, Vörner type; Epidermolytic palmoplantar keratoderma of Voerner; Epidermolytic palmoplantar keratoderma of Vörner; Diffuse erythrodermic palmoplantar keratoderma, Vörner type; Epidermolytic palmoplantar keratoderma of Voerner; Epidermolytic palmoplantar keratoderma of Vörner; EPPK; Hyperkeratosis palmoplantar localized epidermolytic; Tylosis; Keratosis of Greither See More
Categories:
This disease is grouped under:

This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.

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Medical Terms Other Names
Learn More:
HPO ID
80%-99% of people have these symptoms
Erythema 0010783
Localized epidermolytic hyperkeratosis 0007559
Palmoplantar keratoderma
Thickening of palms and soles
0000982
Verrucae
Warts
0200043
30%-79% of people have these symptoms
Abnormal fingernail morphology
Abnormal fingernails
Abnormality of the fingernails
[ more ]
0001231
Eczema 0000964
Hyperhidrosis
Excessive sweating
Increased sweating
Profuse sweating
Sweating
Sweating profusely
Sweating, increased
[ more ]
0000975
Percent of people who have these symptoms is not available through HPO
Autosomal dominant inheritance 0000006
Increased circulating IgE level 0003212
Palmoplantar hyperkeratosis
Thickening of the outer layer of the skin of the palms and soles
0000972
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Last updated: 7/1/2020

Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.

Patient Registry

  • A registry supports research by collecting of information about patients that share something in common, such as being diagnosed with Epidermolytic palmoplantar keratoderma. The type of data collected can vary from registry to registry and is based on the goals and purpose of that registry. Some registries collect contact information while others collect more detailed medical information. Learn more about registries.

    Registries for Epidermolytic palmoplantar keratoderma:
    The National Registry for Ichthyosis & Related Skin Disorders
     

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

In-Depth Information

  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. 
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.

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