National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Steatocystoma multiplex



I have steatocystoma multiplex. This condition mostly affects my arms and legs. Is there any treatment for this?

Treatment options for steatocystoma multiplex are limited and have had varying degrees of success. The most effective treatment method is thought to be removal of cysts by surgery.  However, cosmetic concerns, time, cost, and pain need to be considered because affected individuals often have multiple cysts.[1]  In many cases, small incisions (cuts into the skin) allow the cyst and its contents to be removed through the opening.[2]  Other treatment options include medications such as oral isotretinoin to temporarily shrink the cysts and reduce inflammation or oral antibiotics (tetracycline and derivatives) to reduce redness and swelling. Other procedures may include draining cysts through a procedure called aspirationliquid nitrogen cryotherapydermabrasion, and carbon dioxide laser therapy.[2][3][1][4]

Laser treatments may be useful for patients with numerous cysts in whom removal and drainage is not a realistic choice and for whom other treatments have failed to improve the condition.[1]
Last updated: 8/2/2016

We hope this information is helpful. We strongly recommend you discuss this information with your doctor. If you still have questions, please contact us.

Warm regards,
GARD Information Specialist

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  1. Moody MN, Landau JM, Goldberg LH, Friedman PM. 1,450-nm Diode Laser in Combination with the 1550-nm Fractionated Erbium-Doped Fiber Laser for the Treatment of Steatocystoma Multiplex: A Case Report. Dermatol Surg. April 2012; Epub:
  2. Oakley A. Steatocystoma multiplex. DermNet NZ. February 22, 2014; http://www.dermnetnz.org/lesions/steatocystoma-multiplex.html.
  3. Lee KK, Mehrany K, Swanson NA. Recognition and Treatment of Skin Lesions. In: Cummings. Otolaryngology: Head & Neck Surgery, 4th ed. Philadelphia, PA: Mosby, Inc; 2005;
  4. Davey MA. Steatocystoma Multiplex Treatment & Management. Medscape Reference. 2016; http://emedicine.medscape.com/article/1059725-treatment.