National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Medium-chain acyl-coenzyme A dehydrogenase deficiency



I am wondering if there is any information about children suffering from MCADD experiencing white stools for any reason related to the metabolic disorder. Is this a sign that my daughter is getting fat build-up on her heart, brain, or liver? Please let me know what you think.

We are not aware of an association between white stool and MCADD, or of reports of people with MCADD having white stools.

Stool color is generally influenced by what a person eats, as well as by the amount of bile in the stool. Bile is a yellow-green fluid produced by the liver that digests fats. As bile travels through the gastrointestinal tract, it becomes chemically altered by enzymes, which normally change the color from green to brown.[1]

Light-colored, white, or clay-colored stool could indicate a lack of bile in the stool. This is sometimes due to having a bile duct obstruction, or another problem with how the liver is functioning. Certain medications can also cause light-colored stools such as large doses of bismuth subsalicylate (Kaopectate, Pepto-Bismol) and other anti-diarrheal drugs.[1]

Any sudden, or gradual, persistent changes in stool color should be evaluated by a medical professional to make sure the changes are not caused by an underlying medical problem.
Last updated: 7/8/2014

We hope this information is helpful. We strongly recommend you discuss this information with your doctor. If you still have questions, please contact us.

Warm regards,
GARD Information Specialist

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  1. Michael F. Picco. Stool color: when to worry. Mayo Clinic. October 12, 2012; Accessed 7/7/2014.