National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Prader-Willi syndrome



For individuals with Prader Willi syndrome, how does this condition affect their lives when they get older?

Children with Prader-Willi syndrome (PWS) can be mainstreamed into the classroom environment, although they need additional speech therapy and should have additional physical activity periods in place of rest periods. They generally need a structured environment and may need a smaller classroom size for individual attention.[1]

People with PWS usually reach adulthood and are able to function in a group home setting, performing vocational work, or attending community college classes.[1] According to the Prader-Willi Syndrome Association, people with PWS can expect to accomplish many of the things their peers do. However, they do need a significant amount of support from their families and from school, work, and residential service providers. Even those with IQs in the normal range need lifelong diet supervision and protection from food availability.[2]

Complications that could affect the quality of life and potentially shorten life expectancy include those relating to hypogonadism, behavioral or psychological issues, and morbid obesity.[1]
Last updated: 1/6/2015

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  1. Ann Scheimann. Prader-Willi Syndrome. Medscape. March 18, 2014; http://emedicine.medscape.com/article/947954-overview. Accessed 1/6/2015.
  2. FAQ. Prader-Willi Syndrome Association. 2015; http://www.pwsausa.org/about-pws/faq. Accessed 9/23/2015.