Allan-Herndon-Dudley syndrome

Allan-Herndon-Dudley syndrome is a disorder of brain development that causes moderate to severe intellectual disability and problems with movement. This condition, which occurs exclusively in males, disrupts development from before birth. Although affected males have speech and a limited ability to communicate, they seem to enjoy interaction with others. Allan-Herndon-Dudley syndrome is caused by mutations in the SLC16A2 gene. It is inherited in an X-linked recessive manner.^[1] 

No. We were unable to find any reports of cleft lip and/or palate in people affected by Allan-Herndon-Dudley syndrome.

Allan-Herndon-Dudley syndrome causes moderate to severe intellectual disability and problems with movement. People with this syndrome also have impaired speech and a limited ability to communicate. Most children have weak muscle tone (hypotonia) and underdevelopment of many muscles (muscle hypoplasia). As they get older, they often develop joint deformities called contractures, which restrict the movement of certain joints. Abnormal muscle stiffness (spasticity), muscle weakness, and involuntary movements of the arms and legs also limit mobility. As a result, many people with Allan-Herndon-Dudley syndrome are unable to walk independently and use a wheelchair in adulthood.^[1]