National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Dandy-Walker complex



What is the life expectancy of someone with Dandy-Walker complex?

The long-term outlook for people with Dandy-Walker complex depends on the symptoms that are caused by the changes in the structures of the brain. The long-term outlook also depends on whether Dandy-Walker complex occurs alone (isolated) or whether there is an underlying genetic syndrome that may cause other health problems. Because the differences in brain structure and the presence of an underlying genetic syndrome may affect the signs and symptoms or life expectancy that a person has, it may be difficult to predict the long-term outlook for people who have Dandy-Walker complex.[1][2]

Some people with Dandy-Walker complex may have physical disabilities or intellectual disabilities. In most cases, infants who have isolated Dandy-Walker variant are more likely to have normal outcomes in the newborn period.[3] 
Last updated: 4/30/2018

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  1. Dandy-Walker Syndrome Information Page. National Institute of Neurological Disorders and Stroke (NINDS). December 20, 2017; https://www.ninds.nih.gov/Disorders/All-Disorders/Dandy-Walker-Syndrome-Information-Page.
  2. Salihu HM, Kornosky JL, and Druschel CM. Dandy-Walker syndrome, associated anomalies and survival through infancy: a population-based study. Fetal Diagn Ther. 2008; 24(2):155-60. http://www.ncbi.nlm.nih.gov/pubmed/18648217.
  3. Harper T, Fordham LA, and Wolfe HM. The fetal Dandy Walker complex: associated anomalies, perinatal outcome and postnatal imaging.. Fetal Diagn Ther. 2007; 22(4):277-281. https://www.ncbi.nlm.nih.gov/pubmed/17369695.