Autosomal recessive Alport syndrome

While there are no official guidelines, there has been some literature published on this topic. In particular, you may find the following articles to be a helpful resource. The articles conclude that carrier mothers with normal kidney function can be donors to a child with Alport syndrome and end‐stage renal failure. The mothers may be at an increased risk for kidney symptoms and complications post-donation. We do recommend that you talk with your healthcare provider regarding these risks. Ultimately, decisions regarding organ donation are up to the particular transplant program, and requirements can vary between programs. 

Yachnin T et al. The mother of an Alport's syndrome patient: a safe kidney donor? Nephrol. Dial. Transplant. 2002;17(4):683-684.

Sessa A et al. Renal transplantation from living donor parents in two brothers with Alport syndrome. Can asymptomatic female carriers of the Alport gene be accepted as kidney donors? Nephron. 1995;70(1):106-9.