National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Diffuse idiopathic skeletal hyperostosis

Back to List of Questions
What type of medication used long-term can contribute to diffuse idiopathic skeletal hyperostosis (DISH)?
Long-term use of medications called retinoids, such as isotretinoin, which are similar to vitamin A, can increase the risk of diffuse idiopathic skeletal hyperostosis (DISH). It is unclear whether high intake of vitamin A itself increases the risk.[1][2]
Last updated: 5/11/2015

We hope this information is helpful. We strongly recommend you discuss this information with your doctor. If you still have questions, please contact us.

Warm regards,
GARD Information Specialist

Please see our Disclaimer.

  1. Diffuse idiopathic skeletal hyperostosis (DISH). Mayo Foundation for Medical Education and Research. November 2, 2012; http://www.mayoclinic.com/print/diffuse-idiopathic-skeletal-hyperostosis/DS00740/DSECTION=all&METHOD=print. Accessed 11/17/2013.
  2. Helfgott SM. Diffuse idiopathic skeletal hyperostosis (DISH). UpToDate. June 7, 2017; http://www.uptodate.com/contents/diffuse-idiopathic-skeletal-hyperostosis-dish.