National Center for Advancing and Translational Sciences Genetic and Rare Diseases Information Center, a program of the National Center for Advancing and Translational Sciences

Omsk hemorrhagic fever



Other Names:
OHF
Categories:

Omsk hemorrhagic fever (OHF), caused by Omsk hemorrhagic fever virus (OHFV), is an infection that occurs primarily in the western Siberia regions of Omsk, Novosibirsk, Kurgan and Tyumen. People can become infected from tick bites, or from contact with the blood, feces, or urine of an infected or dead animal (most commonly a rodent who was infected by a tick). Human exposure may also occur from contaminated water, in a laboratory setting, or through the milk of infected goats or sheep. No person-to-person transmission has been documented.[1]

The first signs and symptoms of OHF may begin between 3 to 8 days after exposure and may include chills, fever, nausea, headache, and severe muscle pain. Other symptoms that may occur 3 to 4 days after the first symptoms begin include vomiting, other gastrointestinal problems, and bleeding problems.[1][2] In rare cases, OHF can cause hearing loss, hair loss, and behavioral or psychological problems.[1]
 
There is no specific treatment for OHF, but important aspects of management include hydration and taking usual precautions for people with bleeding disorders. Some people with OHF recover within 2 weeks with no complications. However, others experience a second episode of symptoms, including fever and encephalitis, about 3 weeks after the initial onset of symptoms. In up to 3% of people with OHF, the infection is fatal.[1]
Last updated: 5/7/2018

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

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In-Depth Information

  • The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
  • Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.

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  1. Omsk Hemorrhagic Fever (OHF). Centers for Disease Control and Prevention (CDC). December 9, 2013; https://www.cdc.gov/vhf/omsk/index.html.
  2. Omsk hemorrhagic fever. Orphanet. https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=en&Expert=319266. Accessed 5/7/2018.