Though clinical findings may be vague and unspecific, there are some tests that are useful if a hamate fracture is suspected.

Suspicion should be high in young athletes with chronic pain along the ulnar aspect of the wrist. Chronic wrist pain is common with a hook of the hamate fracture, with tenderness and exquisite pain over the hypothenar area. Paresthesias along the ring and small finger are relatively common in chronic disease.[16] Delayed medical consultation is not uncommon. 

Because of its relation to higher energy trauma and associated injuries, the body of the hamate fracture diagnosis tends to be acute. Swelling and tenderness over the dorsal ulnar wrist frequently present in hamate body fractures.

Weakened grip strength is typical. Grasp maneuvers provoke pain along the ulnar side of the wrist. Fourth and fifth metacarpal pain is related to hamate injuries; even metacarpal deformity may be an indirect sign of the body of the hamate fracture.

Pull test: in the hook of the hamate fractures, active flexion of distal interphalangeal joints of the ring and small finger may cause pain. This phenomenon is the result of flexor tendons deforming forces attached at the fracture site.[17][18]

Initial radiographs include anteroposterior and lateral wrist views. The overlapping of the hook of the hamate and its body is known as the "ring sign," a normal finding in the anteroposterior view. In some hook fractures, the so-called "ring sign" may be disrupted. Other signs that are visible in the anteroposterior view are loss of cortical density at the base of the hook and even absence of the hook.[19] Body fractures are usually visible in standard lateral projection or on CT scan. 

Nevertheless, standard radiographs posses a high rate of false negatives, with a 70% sensitivity.[20][21] Specific views include carpal tunnel projection and semisupine oblique radially deviated projection.[22] CT scan is often necessary to reach proper diagnosis (100% sensitivity).[20] MRI scan is only necessary for chronic disease (avascular necrosis)

If a surgical procedure is required, routine blood work should be performed based on the patient's history and physical exam. The complexity of the surgical procedure is also a required element for which the surgeon must account.

Surgical indications: displaced fractures, nonunion, ulnar nerve compression, median nerve compression, ulnar artery compression, tendon rupture and metacarpal subluxation. 

• Hook fractures:
  • Acute, nondisplaced: Immobilization, ulnar gutter cast for six weeks. There is still debate whether patients may profit from initial surgical treatment in this type of fractures. Sport players will usually benefit from early surgical management, returning to sports activities in three months.
  • Acute, displaced: Excision of a bony fragment is the gold standard procedure. Open reduction and internal fixation (screws or Kirschner wires) is another proven treatment. Both alternatives showed similar clinical results.[23]
  • Chronic pain, nonunion: These signs require fracture pinning with bone grafting.

•  Body fractures:
  • Acute, nondisplaced: Immobilization, six-week cast.[24]
  • Acute, displaced: Open reduction and internal fixation (Kirschner wires, grid plate, or headless compression screws).[25]

Surgical tech tips:

• The motor branch of the ulnar nerve must be clearly spotted and retracted before hook excision or drilling.

• After fractured fragment excision, periosteum closure should be over the base of the remaining body to protect the ulnar nerve and tendons.

Ulnar flexor carpi tendinitis and triangular fibrocartilage complex injuries are a common misdiagnosis.[11] A hamate fracture accompanies a small percentage (1 to 2%) of distal radius fracture.[26]

Other differential diagnoses include:

• Bipartite hamate
• Scaphoid fracture
• Capitate fracture
• Triquetrum fracture
• Pisiform fracture
• Ligamentous injuries (without fracture)
• Carpal bone dislocations

Fractures treated conservatively should generally heal in 8 weeks. Non-displaced hook fractures treated conservatively have a 50% rate of nonunion. Symptomatic nonunion will require further surgical treatment. Surgical treatment (fragment excision or ORIF) provides a more rapid return to daily activities and sports.[27]

• Nonunion
• Posttraumatic arthritis
• Avascular necrosis in proximal pole (body fractures)
• Ulnar nerve compression (Guyon´s canal)
• Carpal tunnel syndrome
• Flexor digitorum profundus tendon rupture
• Ulnar artery thrombosis (hypothenar hammer syndrome)
• Ulnar artery compression
• Residual instability of fourth and/or fifth metacarpals

Physical therapy is mandatory. In the case of conservative treatment, occupational therapy should beg¡n right after cast removal. If ORIF is the preferred method, therapy should begin after a 3-week immobilization protocol. Hook excisions may start early therapy. Rehabilitation protocol should last 4 to 6 weeks.

Patients should be aware of chronic pain and osteoarthritis as common consequences of hamate fractures. Smoking cessation is always a recommendation for fracture healing.  

Radiologic knowledge on this infrequent injuries is crucial to reach a proper diagnosis. General practitioners, including nurse practitioners and PAs, should be aware of the high rate of misdiagnoses. Orthopedic surgeons should provide information regarding specific X-ray views and physical examination. This approach leads to interprofessional teamwork. Patients must receive counsel for further treatment options, especially those involved in sports.   

When diagnosing and managing hamate fractures, the entire interprofessional team has to communicate across disciplinary lines for the patient's benefit. Clinicians, including GPs, NPs, and PAs will most likely diagnose the injury specialists to include orthopedists and radiologists will often guide diagnosis and treatment plans. Nursing will assist in surgery and prep the patient. Initially, pain management may be an issue, and the pharmacists can recommend optimal pharmaceutical therapy to decrease pain while avoiding opioid overuse. The pharmacists can also report back to nursing or the managing clinician regarding potential interactions and side effects. Post-surgery, the physical and/or occupational therapist will guide rehab, and report back to the other members of the team as to the progress or stagnation/regression of the rehabilitation process. All these disciplines must collaborate across interprofessional lines for optimal patient treatment. [Level 5]