Pelvic floor prolapse is the herniation of the pelvic organs through the perineum. Depending on the pelvic organ involved, pelvic prolapse further categorizes into the anterior compartment containing urinary bladder(cystocele), the middle compartment containing uterine or vaginal prolapse (uterus or vagina), or the posterior compartment containing either the small bowel loops (enterocele) or rectum (rectocele). Pelvic prolapse is very common among multiparous women over 50, affecting approximately 50% of women over age 50.[1] The patients present with symptoms of stress fecal or urinary incontinence, uterine prolapse, constipation, or incomplete defecation. Besides, pelvic prolapse can negatively impact the patient's body image and sexuality. Pelvic prolapse treatments range from non-surgical approaches like Kegel exercise and pessary to various surgical procedures.[2] Treatments of pelvic prolapse significantly contribute to the healthcare cost in the United States, estimated at approximately $300 million from 2005 to 2006.[3]

Pelvic floor prolapse is most often clinically diagnosed through physical exams and medical history. Imaging plays a limited role in evaluating mild cases of pelvic prolapse that involve a single pelvic compartment and organ. Nonetheless, translabial ultrasound and dynamic pelvic MRI (MR defecography) serve as valuable tools in diagnosing pelvic prolapse in complex cases involving multiple compartments and multiple pelvic organs. Also, pelvic MRI provides pre-operative planning for complex cases. The article will discuss translabial ultrasound and dynamic pelvic MRI in the evaluation of pelvic prolapse.[4]

The pelvic anatomy divides into three compartments: anterior, middle, and posterior. The anterior compartment contains the bladder and urethra. The vagina and uterus are within the middle compartment. Finally, the posterior compartment contains the sigmoid colon, rectum, and anal canal.[5]

The pelvic muscles, ligaments, and fascia prevent prolapse of the pelvic organs in each compartment. The most crucial pelvic fascia is endopelvic fascia, and it supports the uterus and vagina. Endopelvic fascia is composed of the uterosacral ligament, parametrium, and paracolpium. Pubocervical fascia is between the anterior vaginal wall and pubis; it supports the bladder. Lastly, the rectovaginal fascia supports the rectum. It situates between the posterior vaginal wall and rectum. The primary supporting pelvic muscles include iliococcygeal, pubococcygeal, and puborectal muscles. These are clearly visible on the pelvic MRI. On the other hand, the pelvic ligaments and fascia are less well appreciated on the MRI, but their dysfunctions can be inferred from the prolapse of pelvic organs in each compartment. In healthy patients, the pelvic muscles, ligaments, and fascia prevent the prolapse of pelvic organs and keep the rectum, vagina, and urethra elevated near the pubic symphysis.

Plain films are usually not appropriate for the evaluation of pelvic prolapse.[6] Barium defecography is in use at some places as a part of the assessment of pelvic floor dysfunctions, however, with the advent of newer and non-ionizing radiation imaging techniques like MR defecography, barium defecography has become largely obsolete. 

Due to concern for radiation exposure and availability of MRI, which provides a better soft-tissue resolution, computed tomography (CT) is usually not appropriate for the evaluation of pelvic prolapse; however, one should look on sagittal abdomen and pelvis images for hint of pelvic floor prolapse by drawing a pubococcygeal line and see for overt prolapse and then recommend a dynamic MRI pelvis (MR Defecogram) for further evaluation.[6]

Dynamic magnetic resonance imaging (MRI) provides an accurate assessment of pelvic prolapse. MRI provides a better anatomic detail compared to the translabial ultrasound and is also useful as a preoperative tool. Furthermore, the MRI examination does not require bowel preparation and does not involve sensitive pelvic exposure. Despite its benefits, the MRI is not widely available, expensive, and contraindicated in patients with MRI incompatible devices or hardware.

The patient lies supine in the MRI scanner. This examination utilizes a 1.5 or 3.0 Tesla magnet. Despite the fact pelvic prolapse is most prominent in the upright position, obtaining the images supine does not significantly compromise the diagnostic accuracy.[7] The study is performed following the administration of warm ultrasound gel per rectally, as this makes the rectal more prominent. The patient is encouraged to retain some urine in the urinary bladder as this will help diagnose cystocele. The duration of the scan is approximately 15 minutes. However, the length of the examination can be longer if additional images are necessary. Typical MRI protocol involves a large field of view in the sagittal plane and a small field of view in the axial plane. Images are obtained during the resting phase, the squeezing or kegel phase, with the Valsalva maneuver (straining phase) and defecation or evacuation phases. Coronal plane images are optional and usually not obtained.[7]

The interpretation of the images involves drawing the following lines: pubococcygeal line, M-Line, H-Line, and the anorectal angle.[8][9] Pubococcygeal line demarcates the level of the pelvic floor. The line is drawn between the inferior border of the pubic symphysis and the last intercoccygeal joint. Pelvic organ prolapse is subjectively assessed at rest, squeezing, or kegel phase, with the Valsalva maneuver, as well as the defecation phase. The degree of pelvic prolapse can be graded based on the depth of the descent below the pubococcygeal line as mild (less than 3 cm), moderate (3 to 6 cm), and severe (greater than 6 cm).[10] H- line defines the anterior-posterior width of the levator hiatus. The line is drawn between the inferior border of the pubic symphysis and the anterior wall of the rectum at the anorectal junction. The normal H- line should measure less than 5 cm. Finally, M-line measure the descendants of the levator hiatus. It is drawn perpendicular to the pubococcygeal line and intersects the inferior portion of the H-line. The normal M-line should measure less than 2 cm. H-line greater than 5 cm and M-line greater than 2 cm at rest or with the Valsalva indicates pelvic muscle weakness. The anorectal junction is an important landmark and helps in measuring the anorectal angle. The anorectal angle is the angle between the anal canal central axis and the posterior border of the distalmost portion of the rectum. The normal anorectal angle is between 108 and 127 degrees during the resting phase and denotes the functioning of the puborectalis muscle. Normally, the angle should open or become more obtuse with straining/Valsalva and defecation by approximately 20 degrees.[8][9] Chronic functional constipation is a significant symptom and can adversely affect one's social and personal life. The technical term for this is dyssynergic defecation or spastic pelvic floor syndrome. This condition characteristically presents by an inappropriate lack of relaxation of the puborectalis and external anal sphincter, leading to the urge of defecation without actual fecal emptying. Treatment includes biofeedback therapy, which uses psychophysiological tracings to improve physiological responses. Biofeedback therapy has proven to be very useful in these cases.